Circulating platelets present on their membrane some protuberances, placed among the plasma-membrane particles, when examined with F.E. technique. Statistic tests have shown a significant increase in the average number of such protuoerances in the platelets of hypercholesterolemic (15 - and 45 days) rabbits. After i.v. administration of AD (8-mono-chloro carbochromen, a substance with a supposed anti-aggregaging action) the number of the protuberances of circulating platelets in the hypercholesterolemic rabbits approaches to the average values of the normocholesterolemic ones.
Weber, G., Bianciardi, G., Pierli, C., Toti, P. (1979). Modifications of the freeze-cleaved circulating platelet membrane in hypercholesterolemic rabbits, prevented by AD6. THROMBOSIS AND HAEMOSTASIS, 42, 1 [10.1055/s-0039-1687020].
Modifications of the freeze-cleaved circulating platelet membrane in hypercholesterolemic rabbits, prevented by AD6
Bianciardi, Giorgio;Pierli, C.;Toti, P.
1979-01-01
Abstract
Circulating platelets present on their membrane some protuberances, placed among the plasma-membrane particles, when examined with F.E. technique. Statistic tests have shown a significant increase in the average number of such protuoerances in the platelets of hypercholesterolemic (15 - and 45 days) rabbits. After i.v. administration of AD (8-mono-chloro carbochromen, a substance with a supposed anti-aggregaging action) the number of the protuberances of circulating platelets in the hypercholesterolemic rabbits approaches to the average values of the normocholesterolemic ones.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/19931
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