The research followed consist mainly on the use of passive methods for dynamic characterization of soil and building. Local Seismic Response of the construction site and Calibration of FE model of a reinforced concrete building have been performed. Passive seismic measurements have been acquired by two portable seismographs synchronized by each other with GPS antenna. Subsequently, structural verifications (global structural response) have been realized using once the response spectrum estimated from Local Seismic Response and once from technical standards. Finally, confronts between results have been realized at the aim to evaluate the importance of local seismic response of soil.