MAGA, GIOVANNI
MAGA, GIOVANNI
Dipartimento di Biotecnologie, Chimica e Farmacia
A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors
2013-01-01 Mori, Mattia; Tintori, Cristina; Christopher, R. S. A.; Radi, M.; Schenone, S.; Musumeci, F.; Brullo, C.; Sanità, P.; Delle Monache, S.; Angelucci, A.; Kissova, M.; Crespan, E.; Maga, G.; Botta, M.
Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma.
2014-01-01 Tintori, Cristina; Fallacara, A. L.; Radi, Marco; Zamperini, Claudio; Dreassi, Elena; Crespan, E.; Maga, G.; Schenone, S.; Musumeci, F.; Brullo, C.; Richters, A.; Gasparrini, F.; Angelucci, A.; Festuccia, C.; Delle Monache, S.; Rauh, D.; Botta, M.
DDX3X Helicase Inhibitors as a New Strategy to Fight the West Nile Virus Infection
2019-01-01 Brai, Annalaura; Martelli, Francesco; Riva, Valentina; Garbelli, Anna; Fazi, Roberta; Zamperini, Claudio; Pollutri, Alessandro; Falsitta, Lucia; Ronzini, Stefania; Maccari, Laura; Maga, Giovanni; Giannecchini, Simone; Botta, Maurizio
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors
2012-01-01 Botta, Maurizio; Falchi, F.; Garbelli, A.; Samuele, A.; Bernardo, V.; Paolucci, S.; Baldanti, F.; Schenone, S.; Manetti, F.; Maga, G; Botta, M.
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment
2018-01-01 Molinari, Alessio; Fallacara, Anna Lucia; DI MARIA, Salvatore; Zamperini, Claudio; Poggialini, Federica; Musumeci, Francesca; Schenone, Silvia; Angelucci, Adriano; Colapietro, Alessandro; Crespan, Emmanuele; Kissova, Miroslava; Maga, Giovanni; Botta, Maurizio
HCV-targeted Antivirals: Current Status and Future Challenges
2014-01-01 Gemma, Sandra; Brogi, Simone; Novellino, Ettore; Campiani, Giuseppe; Maga, Giovanni; Brindisi, Margherita; Butini, Stefania
NEW 4-SUBSTITUTED DERIVATIVES OF PYRAZOLO[3,4-D PYRIMIDINE AND PYRROLO[2,3-D]PYRIMIDINE AND USES THEREOF
2010-01-01 Schenone, Silvia; Bondavalli, Francesco; Bruno, Olga; Botta, Maurizio; Manetti, Fabrizio; Radi, Marco; Santucci, Alessandra; Maga, Giovanni; Bologna, Mauro; Angelucci, Adriano; Santucci, Annalisa; Spreafico, Adriano; Carraro, Fabio; Borlak, Jurgen
NEW 4-SUBSTITUTED DERIVATIVES OF PYRAZOLO[3,4-D PYRIMIDINE AND PYRROLO[2,3-D]PYRIMIDINE AND USES THEREOF | [NOUVEAUX DÉRIVÉS 4-SUBSTITUÉS DE LA PYRAZOLO[3,4-D]PYRIMIDINE ET DE LA PYRROLO[2,3-D]PYRIMIDINE ET LEURS UTILISATIONS]
2009-01-01 Schenone, Silvia; Bondavalli, Francesco; Bruno, Olga; Botta, Maurizio; Manetti, Fabrizio; Radi, Marco; Santucci, Alessandra; Maga, Giovanni; Bologna, Mauro; Angelucci, Adriano; Santucci, Annalisa; Spreafico, Adriano; Carraro, Fabio; Borlak, Jurgen
Parallel solution phase synthesis of 4-dialkylamino-2-methylsulfonyl-6-vinylpyrimidines
2005-01-01 Radi, M.; Petricci, E.; Maga, G.; Corelli, F.; Botta, M.
Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors
2013-01-01 Vignaroli, Giulia; Zamperini, Claudio; Dreassi, Elena; Radi, Marco; Angelucci, A.; Sanità, P.; Crespan, Emmanuele; Kissova, M.; Maga, Giovanni; Schenone, S.; Musumeci, F.; Botta, Maurizio
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity
2005-01-01 Fattorusso, Caterina; Gemma, Sandra; Butini, Stefania; Huleatt, Paul; Catalanotti, Bruno; Persico, Marco; De Angelis, Meri; Fiorini, Isabella; Nacci, Vito; Ramunno, Anna; Rodriquez, Manuela; Greco, Giovanni; Novellino, Ettore; Bergamini, Alberto; Marini, Stefano; Coletta, Massimo; Maga, Giovanni; Spadari, Silvio; Campiani, Giuseppe
Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X
2019-01-01 Brai, Annalaura; Ronzini, Stefania; Riva, Valentina; Botta, Lorenzo; Zamperini, Claudio; Borgini, Matteo; Trivisani, Claudia Immacolata; Garbelli, Anna; Pennisi, Carla; Boccuto, Adele; Saladini, Francesco; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio
System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2
2021-01-01 Vicenti, Ilaria; Martina, Maria Grazia; Boccuto, Adele; De Angelis, Marta; Giavarini, Giorgia; Dragoni, Filippo; Marchi, Serena; Trombetta, Claudia Maria; Crespan, Emmanuele; Maga, Giovanni; Eydoux, Cecilia; Decroly, Etienne; Montomoli, Emanuele; Nencioni, Lucia; Zazzi, Maurizio; Radi, Marco
Towards Innovative Antibacterial Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect
2022-01-01 Martina, Maria Grazia; Sannio, Filomena; Crespan, Emmanuele; Pavone, Marialaura; Simoncini, Alice; Barbieri, Francesca; Perini, Cecilia; Pesce, Emanuela; Maga, Giovanni; Pedemonte, Nicoletta; Docquier, Jean-Denis; Radi, Marco
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors | 1-gen-2013 | Mori, Mattia; Tintori, Cristina; Christopher, R. S. A.; Radi, M.; Schenone, S.; Musumeci, F.; Brullo, C.; Sanità, P.; Delle Monache, S.; Angelucci, A.; Kissova, M.; Crespan, E.; Maga, G.; Botta, M. | - | |
| Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma. | 1-gen-2014 | Tintori, Cristina; Fallacara, A. L.; Radi, Marco; Zamperini, Claudio; Dreassi, Elena; Crespan, E.; Maga, G.; Schenone, S.; Musumeci, F.; Brullo, C.; Richters, A.; Gasparrini, F.; Angelucci, A.; Festuccia, C.; Delle Monache, S.; Rauh, D.; Botta, M. | - | |
| DDX3X Helicase Inhibitors as a New Strategy to Fight the West Nile Virus Infection | 1-gen-2019 | Brai, Annalaura; Martelli, Francesco; Riva, Valentina; Garbelli, Anna; Fazi, Roberta; Zamperini, Claudio; Pollutri, Alessandro; Falsitta, Lucia; Ronzini, Stefania; Maccari, Laura; Maga, Giovanni; Giannecchini, Simone; Botta, Maurizio | - | |
| Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors | 1-gen-2012 | Botta, Maurizio; Falchi, F.; Garbelli, A.; Samuele, A.; Bernardo, V.; Paolucci, S.; Baldanti, F.; Schenone, S.; Manetti, F.; Maga, G; Botta, M. | - | |
| Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment | 1-gen-2018 | Molinari, Alessio; Fallacara, Anna Lucia; DI MARIA, Salvatore; Zamperini, Claudio; Poggialini, Federica; Musumeci, Francesca; Schenone, Silvia; Angelucci, Adriano; Colapietro, Alessandro; Crespan, Emmanuele; Kissova, Miroslava; Maga, Giovanni; Botta, Maurizio | - | |
| HCV-targeted Antivirals: Current Status and Future Challenges | 1-gen-2014 | Gemma, Sandra; Brogi, Simone; Novellino, Ettore; Campiani, Giuseppe; Maga, Giovanni; Brindisi, Margherita; Butini, Stefania | - | |
| NEW 4-SUBSTITUTED DERIVATIVES OF PYRAZOLO[3,4-D PYRIMIDINE AND PYRROLO[2,3-D]PYRIMIDINE AND USES THEREOF | 1-gen-2010 | Schenone, Silvia; Bondavalli, Francesco; Bruno, Olga; Botta, Maurizio; Manetti, Fabrizio; Radi, Marco; Santucci, Alessandra; Maga, Giovanni; Bologna, Mauro; Angelucci, Adriano; Santucci, Annalisa; Spreafico, Adriano; Carraro, Fabio; Borlak, Jurgen | - | |
| NEW 4-SUBSTITUTED DERIVATIVES OF PYRAZOLO[3,4-D PYRIMIDINE AND PYRROLO[2,3-D]PYRIMIDINE AND USES THEREOF | [NOUVEAUX DÉRIVÉS 4-SUBSTITUÉS DE LA PYRAZOLO[3,4-D]PYRIMIDINE ET DE LA PYRROLO[2,3-D]PYRIMIDINE ET LEURS UTILISATIONS] | 1-gen-2009 | Schenone, Silvia; Bondavalli, Francesco; Bruno, Olga; Botta, Maurizio; Manetti, Fabrizio; Radi, Marco; Santucci, Alessandra; Maga, Giovanni; Bologna, Mauro; Angelucci, Adriano; Santucci, Annalisa; Spreafico, Adriano; Carraro, Fabio; Borlak, Jurgen | - | |
| Parallel solution phase synthesis of 4-dialkylamino-2-methylsulfonyl-6-vinylpyrimidines | 1-gen-2005 | Radi, M.; Petricci, E.; Maga, G.; Corelli, F.; Botta, M. | - | |
| Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors | 1-gen-2013 | Vignaroli, Giulia; Zamperini, Claudio; Dreassi, Elena; Radi, Marco; Angelucci, A.; Sanità, P.; Crespan, Emmanuele; Kissova, M.; Maga, Giovanni; Schenone, S.; Musumeci, F.; Botta, Maurizio | - | |
| Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity | 1-gen-2005 | Fattorusso, Caterina; Gemma, Sandra; Butini, Stefania; Huleatt, Paul; Catalanotti, Bruno; Persico, Marco; De Angelis, Meri; Fiorini, Isabella; Nacci, Vito; Ramunno, Anna; Rodriquez, Manuela; Greco, Giovanni; Novellino, Ettore; Bergamini, Alberto; Marini, Stefano; Coletta, Massimo; Maga, Giovanni; Spadari, Silvio; Campiani, Giuseppe | - | |
| Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X | 1-gen-2019 | Brai, Annalaura; Ronzini, Stefania; Riva, Valentina; Botta, Lorenzo; Zamperini, Claudio; Borgini, Matteo; Trivisani, Claudia Immacolata; Garbelli, Anna; Pennisi, Carla; Boccuto, Adele; Saladini, Francesco; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio | - | |
| System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2 | 1-gen-2021 | Vicenti, Ilaria; Martina, Maria Grazia; Boccuto, Adele; De Angelis, Marta; Giavarini, Giorgia; Dragoni, Filippo; Marchi, Serena; Trombetta, Claudia Maria; Crespan, Emmanuele; Maga, Giovanni; Eydoux, Cecilia; Decroly, Etienne; Montomoli, Emanuele; Nencioni, Lucia; Zazzi, Maurizio; Radi, Marco | - | |
| Towards Innovative Antibacterial Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect | 1-gen-2022 | Martina, Maria Grazia; Sannio, Filomena; Crespan, Emmanuele; Pavone, Marialaura; Simoncini, Alice; Barbieri, Francesca; Perini, Cecilia; Pesce, Emanuela; Maga, Giovanni; Pedemonte, Nicoletta; Docquier, Jean-Denis; Radi, Marco | - |