GIANNINI, GIUSEPPE
GIANNINI, GIUSEPPE
Dipartimento di Biotecnologie, Chimica e Farmacia
A novel bioresponsive self-immolative spacer based on aza-quinone methide reactivity for the controlled release of thiols, phenols, amines, sulfonamides or amides
2024-01-01 Ermini, Elena; Brai, Annalaura; Cini, Elena; Finetti, Federica; Giannini, Giuseppe; Padula, Daniele; Paradisi, Lucrezia; Poggialini, Federica; Trabalzini, Lorenza; Tolu, Paola; Taddei, Maurizio
Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation
2018-01-01 Cini, Elena; Faltoni, Valentina; Petricci, Elena; Taddei, Maurizio; Salvini, Laura; Giannini, Giuseppe; Vesci, Loredana; Milazzo, Ferdinando Maria; Anastasi, Anna Maria; Battistuzzi, Gianfranco; De Santis, Rita
ErbB2 targeted epigenetic modulation: anti-tumor efficacy of the ADC Trastuzumab-HDACi ST8176AA1
2020-01-01 Maria Milazzo, Ferdinando; Vesci, Loredana; Maria Anastasi, Anna; Chiapparino, Caterina; Rosi, Antonio; Giannini, Giuseppe; Taddei, Maurizio; Cini, Elena; Faltoni, Valentina; Petricci, Elena; Battistuzzi, Gianfranco; Salvini, Laura; Carollo, Valeria; De Santis, Rita
Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo
2018-01-01 Vesci, Loredana; Milazzo, Ferdinando Maria; Stasi, Maria Antonietta; Pace, Silvia; Manera, Francesco; Tallarico, Carlo; Cini, Elena; Petricci, Elena; Manetti, Fabrizio; De Santis, Rita; Giannini, Giuseppe
Histone Deacetylase Inhibitors-based antibody drug conjugates (ADCs) and use in therapy
2017-01-01 Vesci, Loredana; De Santis, Rita; Maria Milazzo, Ferdinando; Giannini, Giuseppe; Taddei, Maurizio; Faltoni, Valentina; Petricci, Elena
Quinolines and Oxazino-quinoline derivatives as small molecule GLI1 inhibitors identified by virtual screening
2022-01-01 Manetti, Fabrizio; Maresca, Luisa; Crivaro, Enrica; Pepe, Sara; Cini, Elena; Singh, Snigdha; Governa, Paolo; Maramai, Samuele; Giannini, Giuseppe; Stecca, Barbara; Petricci, Elena
Ruthenium-catalyzed synthesis of 5-amino-1,2,3-triazole-4-carboxylates for triazole-based scaffolds: Beyond the Dimroth rearrangement
2015-01-01 Ferrini, Serena; Chandanshive, Jay Zumbar; Lena, Stefano; Franchini, Mauro Comes; Giannini, Giuseppe; Tafi, Andrea; Taddei, Maurizio
Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth
2023-01-01 Maresca, Luisa; Crivaro, Enrica; Migliorini, Francesca; Anichini, Giulia; Giammona, Alessandro; Pepe, Sara; Poggialini, Federica; Vagaggini, Chiara; Giannini, Giuseppe; Sestini, Serena; Borgognoni, Lorenzo; Lapucci, Andrea; Dreassi, Elena; Taddei, Maurizio; Manetti, Fabrizio; Petricci, Elena; Stecca, Barbara
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A novel bioresponsive self-immolative spacer based on aza-quinone methide reactivity for the controlled release of thiols, phenols, amines, sulfonamides or amides | 1-gen-2024 | Ermini, Elena; Brai, Annalaura; Cini, Elena; Finetti, Federica; Giannini, Giuseppe; Padula, Daniele; Paradisi, Lucrezia; Poggialini, Federica; Trabalzini, Lorenza; Tolu, Paola; Taddei, Maurizio | - | |
| Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation | 1-gen-2018 | Cini, Elena; Faltoni, Valentina; Petricci, Elena; Taddei, Maurizio; Salvini, Laura; Giannini, Giuseppe; Vesci, Loredana; Milazzo, Ferdinando Maria; Anastasi, Anna Maria; Battistuzzi, Gianfranco; De Santis, Rita | - | |
| ErbB2 targeted epigenetic modulation: anti-tumor efficacy of the ADC Trastuzumab-HDACi ST8176AA1 | 1-gen-2020 | Maria Milazzo, Ferdinando; Vesci, Loredana; Maria Anastasi, Anna; Chiapparino, Caterina; Rosi, Antonio; Giannini, Giuseppe; Taddei, Maurizio; Cini, Elena; Faltoni, Valentina; Petricci, Elena; Battistuzzi, Gianfranco; Salvini, Laura; Carollo, Valeria; De Santis, Rita | - | |
| Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo | 1-gen-2018 | Vesci, Loredana; Milazzo, Ferdinando Maria; Stasi, Maria Antonietta; Pace, Silvia; Manera, Francesco; Tallarico, Carlo; Cini, Elena; Petricci, Elena; Manetti, Fabrizio; De Santis, Rita; Giannini, Giuseppe | - | |
| Histone Deacetylase Inhibitors-based antibody drug conjugates (ADCs) and use in therapy | 1-gen-2017 | Vesci, Loredana; De Santis, Rita; Maria Milazzo, Ferdinando; Giannini, Giuseppe; Taddei, Maurizio; Faltoni, Valentina; Petricci, Elena | - | |
| Quinolines and Oxazino-quinoline derivatives as small molecule GLI1 inhibitors identified by virtual screening | 1-gen-2022 | Manetti, Fabrizio; Maresca, Luisa; Crivaro, Enrica; Pepe, Sara; Cini, Elena; Singh, Snigdha; Governa, Paolo; Maramai, Samuele; Giannini, Giuseppe; Stecca, Barbara; Petricci, Elena | - | |
| Ruthenium-catalyzed synthesis of 5-amino-1,2,3-triazole-4-carboxylates for triazole-based scaffolds: Beyond the Dimroth rearrangement | 1-gen-2015 | Ferrini, Serena; Chandanshive, Jay Zumbar; Lena, Stefano; Franchini, Mauro Comes; Giannini, Giuseppe; Tafi, Andrea; Taddei, Maurizio | - | |
| Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth | 1-gen-2023 | Maresca, Luisa; Crivaro, Enrica; Migliorini, Francesca; Anichini, Giulia; Giammona, Alessandro; Pepe, Sara; Poggialini, Federica; Vagaggini, Chiara; Giannini, Giuseppe; Sestini, Serena; Borgognoni, Lorenzo; Lapucci, Andrea; Dreassi, Elena; Taddei, Maurizio; Manetti, Fabrizio; Petricci, Elena; Stecca, Barbara | - |