OROFINO, FRANCESCO
OROFINO, FRANCESCO
Dipartimento di Biotecnologie, Chimica e Farmacia
AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma
2020-01-01 Molinari, Alessio; Iovenitti, Giulia; Mancini, Arianna; Luca Gravina, Giovanni; Chebbi, Monia; Caruana, Maura; Vignaroli, Giulia; Orofino, Francesco; Rango, Enrico; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Botta, Maurizio
Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors
2020-01-01 Fiorucci, Diego; Milletti, Eva; Orofino, Francesco; Brizzi, Antonella; Mugnaini, Claudia; Corelli, Federico
Design and synthesis of a novel inhibitor of T. Viride chitinase through an in silico target fishing protocol
2017-01-01 Maccari, Giorgio; Deodato, Davide; Fiorucci, Diego; Orofino, Francesco; Truglio, Giuseppina I.; Pasero, Carolina; Martini, Riccardo; De Luca, Filomena; Docquier, Jean-Denis; Botta, Maurizio
Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors
2023-01-01 Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena
Focused library of phenyl-fused macrocyclic amidinoureas as antifungal agents
2022-01-01 Balestri, Lorenzo J. I.; D'Agostino, Ilaria; Rango, Enrico; Vagaggini, Chiara; Marchitiello, Rosalba; Mariotti, Melinda; Casian, Alexandru; Deodato, Davide; Truglio, Giuseppina I.; Orofino, Francesco; Sanguinetti, Maurizio; Bugli, Francesca; Botta, Lorenzo; Dreassi, Elena
Identification, synthesis and biological activity of alkyl-guanidine oligomers as potent antibacterial agents
2017-01-01 Zamperini, C.; Maccari, G.; Deodato, D.; Pasero, Carolina; D'Agostino, Ilaria; Orofino, Francesco; De Luca, F.; Dreassi, E.; Docquier, J. D.; Botta, M.
In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains
2020-01-01 Orofino, F.; Truglio, G. I.; Fiorucci, D.; D'Agostino, I.; Borgini, M.; Poggialini, F.; Zamperini, C.; Dreassi, E.; Maccari, L.; Torelli, R.; Martini, C.; Bernabei, M.; Meis, J. F.; Khandelwal, N. K.; Prasad, R.; Sanguinetti, M.; Bugli, F.; Botta, M.
MACROCYCLIC AMIDINOUREAS, A VALID SCAFFOLD FOR ANTIFUNGAL AND CHITINASE INHIBITING COMPOUNDS
2018-01-01 Orofino, Francesco
Preface [Neglected Diseases: Extensive Space for Modern Drug Discovery]
2018-01-01 Orofino, Francesco; Botta, Maurizio
Viral Envelope Membrane: A Special Entry Pathway and a Promising Drug Target
2021-01-01 Palombi, Nastasja; Brai, Annalaura; Gerace, Martina; DI MARIA, Salvatore; Orofino, Francesco; Corelli, Federico
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma | 1-gen-2020 | Molinari, Alessio; Iovenitti, Giulia; Mancini, Arianna; Luca Gravina, Giovanni; Chebbi, Monia; Caruana, Maura; Vignaroli, Giulia; Orofino, Francesco; Rango, Enrico; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Botta, Maurizio | - | |
| Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors | 1-gen-2020 | Fiorucci, Diego; Milletti, Eva; Orofino, Francesco; Brizzi, Antonella; Mugnaini, Claudia; Corelli, Federico | - | |
| Design and synthesis of a novel inhibitor of T. Viride chitinase through an in silico target fishing protocol | 1-gen-2017 | Maccari, Giorgio; Deodato, Davide; Fiorucci, Diego; Orofino, Francesco; Truglio, Giuseppina I.; Pasero, Carolina; Martini, Riccardo; De Luca, Filomena; Docquier, Jean-Denis; Botta, Maurizio | - | |
| Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors | 1-gen-2023 | Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena | - | |
| Focused library of phenyl-fused macrocyclic amidinoureas as antifungal agents | 1-gen-2022 | Balestri, Lorenzo J. I.; D'Agostino, Ilaria; Rango, Enrico; Vagaggini, Chiara; Marchitiello, Rosalba; Mariotti, Melinda; Casian, Alexandru; Deodato, Davide; Truglio, Giuseppina I.; Orofino, Francesco; Sanguinetti, Maurizio; Bugli, Francesca; Botta, Lorenzo; Dreassi, Elena | - | |
| Identification, synthesis and biological activity of alkyl-guanidine oligomers as potent antibacterial agents | 1-gen-2017 | Zamperini, C.; Maccari, G.; Deodato, D.; Pasero, Carolina; D'Agostino, Ilaria; Orofino, Francesco; De Luca, F.; Dreassi, E.; Docquier, J. D.; Botta, M. | - | |
| In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains | 1-gen-2020 | Orofino, F.; Truglio, G. I.; Fiorucci, D.; D'Agostino, I.; Borgini, M.; Poggialini, F.; Zamperini, C.; Dreassi, E.; Maccari, L.; Torelli, R.; Martini, C.; Bernabei, M.; Meis, J. F.; Khandelwal, N. K.; Prasad, R.; Sanguinetti, M.; Bugli, F.; Botta, M. | - | |
| MACROCYCLIC AMIDINOUREAS, A VALID SCAFFOLD FOR ANTIFUNGAL AND CHITINASE INHIBITING COMPOUNDS | 1-gen-2018 | Orofino, Francesco | - | |
| Preface [Neglected Diseases: Extensive Space for Modern Drug Discovery] | 1-gen-2018 | Orofino, Francesco; Botta, Maurizio | - | |
| Viral Envelope Membrane: A Special Entry Pathway and a Promising Drug Target | 1-gen-2021 | Palombi, Nastasja; Brai, Annalaura; Gerace, Martina; DI MARIA, Salvatore; Orofino, Francesco; Corelli, Federico | - |