DICHIARA, MARIA
DICHIARA, MARIA
Dipartimento di Biotecnologie, Chimica e Farmacia
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] derivatives as potent and selective sigma receptor ligands: stereochemistry and pharmacological properties
2018-01-01 Amata, Emanuele; Rescifina, Antonio; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Pittalà, Valeria; Montilla-Garcia, A ngeles; Punzo, Francesco; Merino, Pedro; Cobos J., Enrique; Marrazzo, Agostino
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients
2024-01-01 Rossi, Sara; Tatangelo, Vanessa; Dichiara, Maria; Butini, Stefania; Gemma, Sandra; Brogi, Simone; Pasquini, Silvia; Cappello, Martina; Vincenzi, Fabrizio; Varani, Katia; Lopresti, Ludovica; Malchiodi, Margherita; Carrara, Chiara; Gozzetti, Alessandro; Bocchia, Monica; Marotta, Giuseppe; Patrussi, Laura; Carullo, Gabriele; Baldari, Cosima T.; Campiani, Giuseppe
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review
2017-01-01 Floresta, Giuseppe; Pistarà, Venerando; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Prezzavento, Orazio; Rescifina, Antonio
Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products
2024-01-01 Fedeli, Riccardo; Spizzirri, Umile Gianfranco; Aquino, Giovanna; Basilicata, Manuela Giovanna; Pepe, Giacomo; Campiglia, Pietro; Celletti, Silvia; Tudino, Valeria; Dichiara, Maria; Gemma, Sandra; Butini, Stefania; Carullo, Gabriele; Aiello, Francesca; Restuccia, Donatella; Campiani, Giuseppe; Loppi, Stefano
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity
2021-01-01 Romeo, Giuseppe; Ciaffaglione, Valeria; Amata, Emanuele; Dichiara, Maria; Calabrese, Loredana; Vanella, Luca; Sorrenti, Valeria; Grosso, Salvo; D'amico Agata, Grazia; D'Agata, Velia; Intagliata, Sebastiano; Salerno, Loredana
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors
2017-01-01 Amata, Emanuele; Marrazzo, Agostino; Dichiara, Maria; Modica Maria, Nunziata; Salerno, Loredana; Prezzavento, Orazio; Nastasi, Giovanni; Rescifina, Antonio; Romeo, Giuseppe; Pittalà, Valeria
Correction to “Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents”
2022-01-01 Fallica, Antonino Nicolò; Barbaraci, Carla; Amata, Emanuele; Pasquinucci, Lorella; Turnaturi, Rita; Dichiara, Maria; Intagliata, Sebastiano; Gariboldi, Marzia Bruna; Marras, Emanuela; Orlandi, Viviana Teresa; Ferroni, Claudia; Martini, Cecilia; Rescifina, Antonio; Gentile, Davide; Varchi, Greta; Marrazzo, Agostino
Cytotoxicity profiles and neuroprotective properties of the novel ifenprodil analogues as sigma ligands
2023-01-01 Zampieri, Daniele; Calabretti, Antonella; Romano, Maurizio; Fortuna, Sara; Collina, Simona; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Mamolo Maria, Grazia.
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands
2022-01-01 Zampieri, Daniele; Fortuna, Sara; Romano, Maurizio; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Pasquinucci, Lorella; Turnaturi, Rita; Mamolo Maria, Grazia
Design, Synthesis, and Cytotoxic Assessment of New Haloperidol Analogues as Potential Anticancer Compounds Targeting Sigma Receptors
2024-01-01 Zampieri, Daniele; Romano, Maurizio; Fortuna, Sara; Amata, Emanuele; Dichiara, Maria; Cosentino, Giuseppe; Marrazzo, Agostino; Mamolo, Maria Grazia
Designing drugs optimized for both blood–brain barrier permeation and intra-cerebral partition
2024-01-01 Dichiara, Maria; Cosentino, Giuseppe; Giordano, Giorgia; Pasquinucci, Lorella; Marrazzo, Agostino; Costanzo, Giuliana; Amata, Emanuele
Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis
2017-01-01 Rescifina, Antonio; Floresta, Giuseppe; Marrazzo, Agostino; Parenti, Carmela; Prezzavento, Orazio; Nastasi, Giovanni; Dichiara, Maria; Amata, Emanuele
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds
2025-01-01 Cosentino, Giuseppe; Dichiara, Maria; Ambrosio, Francesca Alessandra; Leotta, Claudia Giovanna; Costa, Giosuè; Procopio, Francesca; Costanzo, Giuliana; Raffa, Alessandro; Artacho-Cordón, Antonia; Ruiz-Cantero, M. Carmen; Pasquinucci, Lorella; Marrazzo, Agostino; Pitari, Giovanni Mario; Cobos, Enrique J.; Alcaro, Stefano; Amata, Emanuele
Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity
2023-01-01 De Luca, Laura; Lombardo, Lisa; Mirabile, Salvatore; Marrazzo, Agostino; Dichiara, Maria; Cosentino, Giuseppe; Amata, Emanuele; Gitto, Rosaria
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity
2023-01-01 Dichiara, Maria; Ambrosio, Francesca Alessandra; Lee, Sang Min; Ruiz-Cantero, M. Carmen; Lombino, Jessica; Coricello, Adriana; Costa, Giosuè; Shah, Dhara; Costanzo, Giuliana; Pasquinucci, Lorella; Son, Kyung No; Cosentino, Giuseppe; González-Cano, Rafael; Marrazzo, Agostino; Aakalu, Vinay Kumar; Cobos, Enrique J.; Alcaro, Stefano; Amata, Emanuele
Discovery of first novel sigma/HDACi dual-ligands with a potent in vitro antiproliferative activity
2023-01-01 Barbaraci, Carla; di Giacomo, Viviana; Maruca, Annalisa; Patamia, Vincenzo; Rocca, Roberta; Dichiara, Maria; Di Rienzo, Annalisa; Cacciatore, Ivana; Cataldi, Amelia; Balaha, Marwa; Rapino, Monica; Zagni, Chiara; Zampieri, Daniele; Pasquinucci, Lorella; Parenti, Carmela; Amata, Emanuele; Rescifina, Antonio; Alcaro, Stefano; Marrazzo, Agostino
Discovery, affinity maturation and multimerization of small molecule ligands against human tyrosinase and tyrosinase-related protein 1
2021-01-01 Catalano, Marco; Bassi, Gabriele; Rotondi, Giulia; Khettabi, Lyna; Dichiara, Maria; Murer, Patrizia; Scheuermann, Jörg; Soler-Lopez, Montserrat; Neri, Dario
Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain
2023-01-01 Szczepańska, Katarzyna; Karcz, Tadeusz; Dichiara, Maria; Mogilski, Szczepan; Kalinowska-Tłuścik, Justyna; Pilarski, Bogusław; Leniak, Arkadiusz; Pietruś, Wojciech; Podlewska, Sabina; Popiołek-Barczyk, Katarzyna; Humphrys, Laura J.; Ruiz-Cantero, M. Carmen; Reiner-Link, David; Leitzbach, Luisa; Łażewska, Dorota; Pockes, Steffen; Górka, Michał; Zmysłowski, Adam; Calmels, Thierry; Cobos, Enrique J.; Marrazzo, Agostino; Stark, Holger; Bojarski, Andrzej J.; Amata, Emanuele; Kieć-Kononowicz, Katarzyna
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: design, synthesis, and pharmacological evaluation
2022-01-01 Dichiara, Maria; Artacho-Cordón, Antonia; Turnaturi, Rita; Santos-Caballero, Miriam; González-Cano, Rafael; Pasquinucci, Lorella; Barbaraci, Carla; Rodríguez-Gómez, Isabel; Gómez-Guzmán, Manuel; Marrazzo, Agostino; Cobos J., Enrique; Amata, Emanuele.
Exploiting the power of stereochemistry in drug action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as potent Sigma-1 receptor antagonist
2020-01-01 Turnaturi, Rita; Pasquinucci, Lorella; Chiechio, Santina; Grasso, Margherita; Marrazzo, Agostino; Amata, Emanuele; Dichiara, Maria; Prezzavento, Orazio; Parenti, Carmela
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| (+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] derivatives as potent and selective sigma receptor ligands: stereochemistry and pharmacological properties | 1-gen-2018 | Amata, Emanuele; Rescifina, Antonio; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Pittalà, Valeria; Montilla-Garcia, A ngeles; Punzo, Francesco; Merino, Pedro; Cobos J., Enrique; Marrazzo, Agostino | - | |
| A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients | 1-gen-2024 | Rossi, Sara; Tatangelo, Vanessa; Dichiara, Maria; Butini, Stefania; Gemma, Sandra; Brogi, Simone; Pasquini, Silvia; Cappello, Martina; Vincenzi, Fabrizio; Varani, Katia; Lopresti, Ludovica; Malchiodi, Margherita; Carrara, Chiara; Gozzetti, Alessandro; Bocchia, Monica; Marotta, Giuseppe; Patrussi, Laura; Carullo, Gabriele; Baldari, Cosima T.; Campiani, Giuseppe | - | |
| Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review | 1-gen-2017 | Floresta, Giuseppe; Pistarà, Venerando; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Prezzavento, Orazio; Rescifina, Antonio | - | |
| Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products | 1-gen-2024 | Fedeli, Riccardo; Spizzirri, Umile Gianfranco; Aquino, Giovanna; Basilicata, Manuela Giovanna; Pepe, Giacomo; Campiglia, Pietro; Celletti, Silvia; Tudino, Valeria; Dichiara, Maria; Gemma, Sandra; Butini, Stefania; Carullo, Gabriele; Aiello, Francesca; Restuccia, Donatella; Campiani, Giuseppe; Loppi, Stefano | - | |
| Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity | 1-gen-2021 | Romeo, Giuseppe; Ciaffaglione, Valeria; Amata, Emanuele; Dichiara, Maria; Calabrese, Loredana; Vanella, Luca; Sorrenti, Valeria; Grosso, Salvo; D'amico Agata, Grazia; D'Agata, Velia; Intagliata, Sebastiano; Salerno, Loredana | - | |
| Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors | 1-gen-2017 | Amata, Emanuele; Marrazzo, Agostino; Dichiara, Maria; Modica Maria, Nunziata; Salerno, Loredana; Prezzavento, Orazio; Nastasi, Giovanni; Rescifina, Antonio; Romeo, Giuseppe; Pittalà, Valeria | - | |
| Correction to “Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents” | 1-gen-2022 | Fallica, Antonino Nicolò; Barbaraci, Carla; Amata, Emanuele; Pasquinucci, Lorella; Turnaturi, Rita; Dichiara, Maria; Intagliata, Sebastiano; Gariboldi, Marzia Bruna; Marras, Emanuela; Orlandi, Viviana Teresa; Ferroni, Claudia; Martini, Cecilia; Rescifina, Antonio; Gentile, Davide; Varchi, Greta; Marrazzo, Agostino | - | |
| Cytotoxicity profiles and neuroprotective properties of the novel ifenprodil analogues as sigma ligands | 1-gen-2023 | Zampieri, Daniele; Calabretti, Antonella; Romano, Maurizio; Fortuna, Sara; Collina, Simona; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Mamolo Maria, Grazia. | - | |
| Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands | 1-gen-2022 | Zampieri, Daniele; Fortuna, Sara; Romano, Maurizio; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Pasquinucci, Lorella; Turnaturi, Rita; Mamolo Maria, Grazia | - | |
| Design, Synthesis, and Cytotoxic Assessment of New Haloperidol Analogues as Potential Anticancer Compounds Targeting Sigma Receptors | 1-gen-2024 | Zampieri, Daniele; Romano, Maurizio; Fortuna, Sara; Amata, Emanuele; Dichiara, Maria; Cosentino, Giuseppe; Marrazzo, Agostino; Mamolo, Maria Grazia | - | |
| Designing drugs optimized for both blood–brain barrier permeation and intra-cerebral partition | 1-gen-2024 | Dichiara, Maria; Cosentino, Giuseppe; Giordano, Giorgia; Pasquinucci, Lorella; Marrazzo, Agostino; Costanzo, Giuliana; Amata, Emanuele | - | |
| Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis | 1-gen-2017 | Rescifina, Antonio; Floresta, Giuseppe; Marrazzo, Agostino; Parenti, Carmela; Prezzavento, Orazio; Nastasi, Giovanni; Dichiara, Maria; Amata, Emanuele | - | |
| Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds | 1-gen-2025 | Cosentino, Giuseppe; Dichiara, Maria; Ambrosio, Francesca Alessandra; Leotta, Claudia Giovanna; Costa, Giosuè; Procopio, Francesca; Costanzo, Giuliana; Raffa, Alessandro; Artacho-Cordón, Antonia; Ruiz-Cantero, M. Carmen; Pasquinucci, Lorella; Marrazzo, Agostino; Pitari, Giovanni Mario; Cobos, Enrique J.; Alcaro, Stefano; Amata, Emanuele | - | |
| Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity | 1-gen-2023 | De Luca, Laura; Lombardo, Lisa; Mirabile, Salvatore; Marrazzo, Agostino; Dichiara, Maria; Cosentino, Giuseppe; Amata, Emanuele; Gitto, Rosaria | - | |
| Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity | 1-gen-2023 | Dichiara, Maria; Ambrosio, Francesca Alessandra; Lee, Sang Min; Ruiz-Cantero, M. Carmen; Lombino, Jessica; Coricello, Adriana; Costa, Giosuè; Shah, Dhara; Costanzo, Giuliana; Pasquinucci, Lorella; Son, Kyung No; Cosentino, Giuseppe; González-Cano, Rafael; Marrazzo, Agostino; Aakalu, Vinay Kumar; Cobos, Enrique J.; Alcaro, Stefano; Amata, Emanuele | - | |
| Discovery of first novel sigma/HDACi dual-ligands with a potent in vitro antiproliferative activity | 1-gen-2023 | Barbaraci, Carla; di Giacomo, Viviana; Maruca, Annalisa; Patamia, Vincenzo; Rocca, Roberta; Dichiara, Maria; Di Rienzo, Annalisa; Cacciatore, Ivana; Cataldi, Amelia; Balaha, Marwa; Rapino, Monica; Zagni, Chiara; Zampieri, Daniele; Pasquinucci, Lorella; Parenti, Carmela; Amata, Emanuele; Rescifina, Antonio; Alcaro, Stefano; Marrazzo, Agostino | - | |
| Discovery, affinity maturation and multimerization of small molecule ligands against human tyrosinase and tyrosinase-related protein 1 | 1-gen-2021 | Catalano, Marco; Bassi, Gabriele; Rotondi, Giulia; Khettabi, Lyna; Dichiara, Maria; Murer, Patrizia; Scheuermann, Jörg; Soler-Lopez, Montserrat; Neri, Dario | - | |
| Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain | 1-gen-2023 | Szczepańska, Katarzyna; Karcz, Tadeusz; Dichiara, Maria; Mogilski, Szczepan; Kalinowska-Tłuścik, Justyna; Pilarski, Bogusław; Leniak, Arkadiusz; Pietruś, Wojciech; Podlewska, Sabina; Popiołek-Barczyk, Katarzyna; Humphrys, Laura J.; Ruiz-Cantero, M. Carmen; Reiner-Link, David; Leitzbach, Luisa; Łażewska, Dorota; Pockes, Steffen; Górka, Michał; Zmysłowski, Adam; Calmels, Thierry; Cobos, Enrique J.; Marrazzo, Agostino; Stark, Holger; Bojarski, Andrzej J.; Amata, Emanuele; Kieć-Kononowicz, Katarzyna | - | |
| Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: design, synthesis, and pharmacological evaluation | 1-gen-2022 | Dichiara, Maria; Artacho-Cordón, Antonia; Turnaturi, Rita; Santos-Caballero, Miriam; González-Cano, Rafael; Pasquinucci, Lorella; Barbaraci, Carla; Rodríguez-Gómez, Isabel; Gómez-Guzmán, Manuel; Marrazzo, Agostino; Cobos J., Enrique; Amata, Emanuele. | - | |
| Exploiting the power of stereochemistry in drug action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as potent Sigma-1 receptor antagonist | 1-gen-2020 | Turnaturi, Rita; Pasquinucci, Lorella; Chiechio, Santina; Grasso, Margherita; Marrazzo, Agostino; Amata, Emanuele; Dichiara, Maria; Prezzavento, Orazio; Parenti, Carmela | - |