DICHIARA, MARIA
DICHIARA, MARIA
Dipartimento di Biotecnologie, Chimica e Farmacia
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] derivatives as potent and selective sigma receptor ligands: stereochemistry and pharmacological properties
2018-01-01 Amata, Emanuele; Rescifina, Antonio; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Pittalà, Valeria; Montilla-Garcia, A ngeles; Punzo, Francesco; Merino, Pedro; Cobos J., Enrique; Marrazzo, Agostino
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients
2024-01-01 Rossi, Sara; Tatangelo, Vanessa; Dichiara, Maria; Butini, Stefania; Gemma, Sandra; Brogi, Simone; Pasquini, Silvia; Cappello, Martina; Vincenzi, Fabrizio; Varani, Katia; Lopresti, Ludovica; Malchiodi, Margherita; Carrara, Chiara; Gozzetti, Alessandro; Bocchia, Monica; Marotta, Giuseppe; Patrussi, Laura; Carullo, Gabriele; Baldari, Cosima T.; Campiani, Giuseppe
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review
2017-01-01 Floresta, Giuseppe; Pistarà, Venerando; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Prezzavento, Orazio; Rescifina, Antonio
Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products
2024-01-01 Fedeli, Riccardo; Spizzirri, Umile Gianfranco; Aquino, Giovanna; Basilicata, Manuela Giovanna; Pepe, Giacomo; Campiglia, Pietro; Celletti, Silvia; Tudino, Valeria; Dichiara, Maria; Gemma, Sandra; Butini, Stefania; Carullo, Gabriele; Aiello, Francesca; Restuccia, Donatella; Campiani, Giuseppe; Loppi, Stefano
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity
2021-01-01 Romeo, Giuseppe; Ciaffaglione, Valeria; Amata, Emanuele; Dichiara, Maria; Calabrese, Loredana; Vanella, Luca; Sorrenti, Valeria; Grosso, Salvo; D'amico Agata, Grazia; D'Agata, Velia; Intagliata, Sebastiano; Salerno, Loredana
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors
2017-01-01 Amata, Emanuele; Marrazzo, Agostino; Dichiara, Maria; Modica Maria, Nunziata; Salerno, Loredana; Prezzavento, Orazio; Nastasi, Giovanni; Rescifina, Antonio; Romeo, Giuseppe; Pittalà, Valeria
Cytotoxicity profiles and neuroprotective properties of the novel ifenprodil analogues as sigma ligands
2023-01-01 Zampieri, Daniele; Calabretti, Antonella; Romano, Maurizio; Fortuna, Sara; Collina, Simona; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Mamolo Maria, Grazia.
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands
2022-01-01 Zampieri, Daniele; Fortuna, Sara; Romano, Maurizio; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Pasquinucci, Lorella; Turnaturi, Rita; Mamolo Maria, Grazia
Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis
2017-01-01 Rescifina, Antonio; Floresta, Giuseppe; Marrazzo, Agostino; Parenti, Carmela; Prezzavento, Orazio; Nastasi, Giovanni; Dichiara, Maria; Amata, Emanuele
Discovery, affinity maturation and multimerization of small molecule ligands against human tyrosinase and tyrosinase-related protein 1
2021-01-01 Catalano, Marco; Bassi, Gabriele; Rotondi, Giulia; Khettabi, Lyna; Dichiara, Maria; Murer, Patrizia; Scheuermann, Jörg; Soler-Lopez, Montserrat; Neri, Dario
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: design, synthesis, and pharmacological evaluation
2022-01-01 Dichiara, Maria; Artacho-Cordón, Antonia; Turnaturi, Rita; Santos-Caballero, Miriam; González-Cano, Rafael; Pasquinucci, Lorella; Barbaraci, Carla; Rodríguez-Gómez, Isabel; Gómez-Guzmán, Manuel; Marrazzo, Agostino; Cobos J., Enrique; Amata, Emanuele.
Exploiting the power of stereochemistry in drug action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as potent Sigma-1 receptor antagonist
2020-01-01 Turnaturi, Rita; Pasquinucci, Lorella; Chiechio, Santina; Grasso, Margherita; Marrazzo, Agostino; Amata, Emanuele; Dichiara, Maria; Prezzavento, Orazio; Parenti, Carmela
H2S releasing molecules in pharmaceutical development
2022-01-01 Dichiara, Maria; Amata, Emanuele
Haloperidol Metabolite II Valproate Ester (S)-(-)-MRJF22: preliminary studies as a potential multifunctional agent against uveal melanoma
2021-01-01 Barbaraci, Carla; Giurdanella, Giovanni; Leotta Claudia, Giovanna; Longo, Anna; Amata, Emanuele; Dichiara, Maria; Pasquinucci, Lorella; Turnaturi, Rita; Prezzavento, Orazio; Cacciatore, Ivana; Zuccarello, Elisa; Lupo, Gabriella; Pitari Giovanni, Mario; Anfuso Carmelina, Daniela; Marrazzo, Agostino
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors
2017-01-01 Amata, Emanuele; Marrazzo, Agostino; Dichiara, Maria; Modica Maria, Nunziata; Salerno, Loredana; Prezzavento, Orazio; Nastasi, Giovanni; Rescifina, Antonio; Romeo, Giuseppe; Pittalà, Valeria
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands
2017-01-01 Floresta, Giuseppe; Rescifina, Antonio; Marrazzo, Agostino; Dichiara, Maria; Pistarà, Venerando; Pittalà, Valeria; Prezzavento, Orazio; Amata, Emanuele
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis
2018-01-01 Floresta, Giuseppe; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Salerno, Loredana; Romeo, Giuseppe; Prezzavento, Orazio; Pittalà, Valeria; Rescifina, Antonio
Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5ʹ-monophosphate glycosidase
2018-01-01 Floresta, Giuseppe; Pistarà, Venerando; Amata, Emanuele; Dichiara, Maria; Damigella, Arcangelo; Marrazzo, Agostino; Prezzavento, Orazio; Punzo, Francesco; Rescifina, Antonio
Morphing of ibogaine: A successful attempt into the search for sigma-2 receptor ligands
2019-01-01 Floresta, Giuseppe; Dichiara, Maria; Gentile, Davide; Prezzavento, Orazio; Marrazzo, Agostino; Rescifina, Antonio; Amata, Emanuele
Nitric oxide photo-donor hybrids of ciprofloxacin and norfloxacin: a shift in activity from antimicrobial to anticancer agents
2021-01-01 Fallica Antonino, Nicolò; Barbaraci, Carla; Amata, Emanuele; Pasquinucci, Lorella; Turnaturi, Rita; Dichiara, Maria; Intagliata, Sebastiano; Gariboldi Marzia, Bruna; Marras, Emanuela; Orlandi Viviana, Teresa; Ferroni, Claudia; Martini, Cecilia; Rescifina, Antonio; Gentile, Davide; Varchi, Greta; Marrazzo, Agostino
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| (+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] derivatives as potent and selective sigma receptor ligands: stereochemistry and pharmacological properties | 1-gen-2018 | Amata, Emanuele; Rescifina, Antonio; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Pittalà, Valeria; Montilla-Garcia, A ngeles; Punzo, Francesco; Merino, Pedro; Cobos J., Enrique; Marrazzo, Agostino | - | |
| A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients | 1-gen-2024 | Rossi, Sara; Tatangelo, Vanessa; Dichiara, Maria; Butini, Stefania; Gemma, Sandra; Brogi, Simone; Pasquini, Silvia; Cappello, Martina; Vincenzi, Fabrizio; Varani, Katia; Lopresti, Ludovica; Malchiodi, Margherita; Carrara, Chiara; Gozzetti, Alessandro; Bocchia, Monica; Marotta, Giuseppe; Patrussi, Laura; Carullo, Gabriele; Baldari, Cosima T.; Campiani, Giuseppe | - | |
| Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review | 1-gen-2017 | Floresta, Giuseppe; Pistarà, Venerando; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Prezzavento, Orazio; Rescifina, Antonio | - | |
| Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products | 1-gen-2024 | Fedeli, Riccardo; Spizzirri, Umile Gianfranco; Aquino, Giovanna; Basilicata, Manuela Giovanna; Pepe, Giacomo; Campiglia, Pietro; Celletti, Silvia; Tudino, Valeria; Dichiara, Maria; Gemma, Sandra; Butini, Stefania; Carullo, Gabriele; Aiello, Francesca; Restuccia, Donatella; Campiani, Giuseppe; Loppi, Stefano | - | |
| Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity | 1-gen-2021 | Romeo, Giuseppe; Ciaffaglione, Valeria; Amata, Emanuele; Dichiara, Maria; Calabrese, Loredana; Vanella, Luca; Sorrenti, Valeria; Grosso, Salvo; D'amico Agata, Grazia; D'Agata, Velia; Intagliata, Sebastiano; Salerno, Loredana | - | |
| Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors | 1-gen-2017 | Amata, Emanuele; Marrazzo, Agostino; Dichiara, Maria; Modica Maria, Nunziata; Salerno, Loredana; Prezzavento, Orazio; Nastasi, Giovanni; Rescifina, Antonio; Romeo, Giuseppe; Pittalà, Valeria | - | |
| Cytotoxicity profiles and neuroprotective properties of the novel ifenprodil analogues as sigma ligands | 1-gen-2023 | Zampieri, Daniele; Calabretti, Antonella; Romano, Maurizio; Fortuna, Sara; Collina, Simona; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Mamolo Maria, Grazia. | - | |
| Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands | 1-gen-2022 | Zampieri, Daniele; Fortuna, Sara; Romano, Maurizio; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Pasquinucci, Lorella; Turnaturi, Rita; Mamolo Maria, Grazia | - | |
| Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis | 1-gen-2017 | Rescifina, Antonio; Floresta, Giuseppe; Marrazzo, Agostino; Parenti, Carmela; Prezzavento, Orazio; Nastasi, Giovanni; Dichiara, Maria; Amata, Emanuele | - | |
| Discovery, affinity maturation and multimerization of small molecule ligands against human tyrosinase and tyrosinase-related protein 1 | 1-gen-2021 | Catalano, Marco; Bassi, Gabriele; Rotondi, Giulia; Khettabi, Lyna; Dichiara, Maria; Murer, Patrizia; Scheuermann, Jörg; Soler-Lopez, Montserrat; Neri, Dario | - | |
| Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: design, synthesis, and pharmacological evaluation | 1-gen-2022 | Dichiara, Maria; Artacho-Cordón, Antonia; Turnaturi, Rita; Santos-Caballero, Miriam; González-Cano, Rafael; Pasquinucci, Lorella; Barbaraci, Carla; Rodríguez-Gómez, Isabel; Gómez-Guzmán, Manuel; Marrazzo, Agostino; Cobos J., Enrique; Amata, Emanuele. | - | |
| Exploiting the power of stereochemistry in drug action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as potent Sigma-1 receptor antagonist | 1-gen-2020 | Turnaturi, Rita; Pasquinucci, Lorella; Chiechio, Santina; Grasso, Margherita; Marrazzo, Agostino; Amata, Emanuele; Dichiara, Maria; Prezzavento, Orazio; Parenti, Carmela | - | |
| H2S releasing molecules in pharmaceutical development | 1-gen-2022 | Dichiara, Maria; Amata, Emanuele | - | |
| Haloperidol Metabolite II Valproate Ester (S)-(-)-MRJF22: preliminary studies as a potential multifunctional agent against uveal melanoma | 1-gen-2021 | Barbaraci, Carla; Giurdanella, Giovanni; Leotta Claudia, Giovanna; Longo, Anna; Amata, Emanuele; Dichiara, Maria; Pasquinucci, Lorella; Turnaturi, Rita; Prezzavento, Orazio; Cacciatore, Ivana; Zuccarello, Elisa; Lupo, Gabriella; Pitari Giovanni, Mario; Anfuso Carmelina, Daniela; Marrazzo, Agostino | - | |
| Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors | 1-gen-2017 | Amata, Emanuele; Marrazzo, Agostino; Dichiara, Maria; Modica Maria, Nunziata; Salerno, Loredana; Prezzavento, Orazio; Nastasi, Giovanni; Rescifina, Antonio; Romeo, Giuseppe; Pittalà, Valeria | - | |
| Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands | 1-gen-2017 | Floresta, Giuseppe; Rescifina, Antonio; Marrazzo, Agostino; Dichiara, Maria; Pistarà, Venerando; Pittalà, Valeria; Prezzavento, Orazio; Amata, Emanuele | - | |
| Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis | 1-gen-2018 | Floresta, Giuseppe; Amata, Emanuele; Dichiara, Maria; Marrazzo, Agostino; Salerno, Loredana; Romeo, Giuseppe; Prezzavento, Orazio; Pittalà, Valeria; Rescifina, Antonio | - | |
| Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5ʹ-monophosphate glycosidase | 1-gen-2018 | Floresta, Giuseppe; Pistarà, Venerando; Amata, Emanuele; Dichiara, Maria; Damigella, Arcangelo; Marrazzo, Agostino; Prezzavento, Orazio; Punzo, Francesco; Rescifina, Antonio | - | |
| Morphing of ibogaine: A successful attempt into the search for sigma-2 receptor ligands | 1-gen-2019 | Floresta, Giuseppe; Dichiara, Maria; Gentile, Davide; Prezzavento, Orazio; Marrazzo, Agostino; Rescifina, Antonio; Amata, Emanuele | - | |
| Nitric oxide photo-donor hybrids of ciprofloxacin and norfloxacin: a shift in activity from antimicrobial to anticancer agents | 1-gen-2021 | Fallica Antonino, Nicolò; Barbaraci, Carla; Amata, Emanuele; Pasquinucci, Lorella; Turnaturi, Rita; Dichiara, Maria; Intagliata, Sebastiano; Gariboldi Marzia, Bruna; Marras, Emanuela; Orlandi Viviana, Teresa; Ferroni, Claudia; Martini, Cecilia; Rescifina, Antonio; Gentile, Davide; Varchi, Greta; Marrazzo, Agostino | - |