Sfoglia per Autore
Multi‐omics analysis reveals drivers of loss of β‐cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study
2024-01-01 Armenteros, Jose Juan Almagro; Brorsson, Caroline; Johansen, Christian Holm; Banasik, Karina; Mazzoni, Gianluca; Moulder, Robert; Hirvonen, Karoliina; Suomi, Tomi; Rasool, Omid; Bruggraber, Sylvaine F. A.; Marcovecchio, M. Loredana; Hendricks, Emile; Al‐sari, Naba; Mattila, Ismo; Legido‐quigley, Cristina; Suvitaival, Tommi; Chmura, Piotr J.; Knip, Mikael; Schulte, Anke M.; Lee, Jeong Heon; Sebastiani, Guido; Grieco, Giuseppina Emanuela; Elo, Laura L.; Kaur, Simranjeet; Pociot, Flemming; Dotta, Francesco; Tree, Tim; Lahesmaa, Riitta; Overbergh, Lut; Mathieu, Chantal; Peakman, Mark; Brunak, Søren; Null, Null
A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes
2024-01-01 Sebastiani, Guido; Grieco, Giuseppina Emanuela; Bruttini, Marco; Auddino, Stefano; Mori, Alessia; Toniolli, Mattia; Fignani, Daniela; Licata, Giada; Aiello, Elena; Nigi, Laura; Formichi, Caterina; Fernandez-Tajes, Juan; Pugliese, Alberto; Evans-Molina, Carmella; Overbergh, Lut; Tree, Timothy; Peakman, Mark; Mathieu, Chantal; Dotta, Francesco
A plasma miR-193b-365 signature combined with age and glycemic status predicts response to Lactococcus lactis-based antigen-specific immunotherapy in new-onset type 1 diabetes
2023-01-01 Sassi, Gabriele; Licata, Giada; Ventriglia, Giuliana; Wouters, Amber; Lemaitre, Pierre; Seurinck, Ruth; Mori, Alessia; Grieco, Giuseppina Emanuela; Bissenova, Samal; Ellis, Darcy; Caluwaerts, Silvia; Rottiers, Pieter; Vandamme, Niels; Mathieu, Chantal; Dotta, Francesco; Gysemans, Conny; Sebastiani, Guido
Intra-islet insulin synthesis defects are associated with endoplasmic reticulum stress and loss of beta cell identity in human diabetes
2023-01-01 Brusco, Noemi; Sebastiani, Guido; Di Giuseppe, Gianfranco; Licata, Giada; Grieco, Giuseppina E; Fignani, Daniela; Nigi, Laura; Formichi, Caterina; Aiello, Elena; Auddino, Stefano; Quero, Giuseppe; Cefalo, Chiara M A; Cinti, Francesca; Mari, Andrea; Ferraro, Pietro M; Pontecorvi, Alfredo; Alfieri, Sergio; Giaccari, Andrea; Dotta, Francesco; Mezza, Teresa
Angiotensin I-converting enzyme type 2 expression is increased in pancreatic islets of type 2 diabetic donors
2023-01-01 Fignani, Daniela; Pedace, Erika; Licata, Giada; Grieco, Giuseppina Emanuela; Aiello, Elena; de Luca, Carmela; Marselli, Lorella; Marchetti, Piero; Sebastiani, Guido; Dotta, Francesco
Identification and Validation of miR-222-3p and miR-409-3p as Plasma Biomarkers in Gestational Diabetes Mellitus Sharing Validated Target Genes Involved in Metabolic Homeostasis
2022-01-01 Filardi, Tiziana; Catanzaro, Giuseppina; Grieco, Giuseppina Emanuela; Splendiani, Elena; Trocchianesi, Sofia; Santangelo, Carmela; Brunelli, Roberto; Guarino, Elisa; Sebastiani, Guido; Dotta, Francesco; Morano, Susanna; Ferretti, Elisabetta
Circulating microRNAs as clinically useful biomarkers for Type 2 Diabetes Mellitus: miRNomics from bench to bedside
2022-01-01 Grieco, Giuseppina Emanuela; Besharat, Zein Mersini; Licata, Giada; Fignani, Daniela; Brusco, Noemi; Nigi, Laura; Formichi, Caterina; Po, Agnese; Sabato, Claudia; Dardano, Angela; Natali, Andrea; Dotta, Francesco; Sebastiani, Guido; Ferretti, Elisabetta
Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors
2022-01-01 Nigi, Laura; Brusco, Noemi; Grieco, Giuseppina E; Fignani, Daniela; Licata, Giada; Formichi, Caterina; Aiello, Elena; Marselli, Lorella; Marchetti, Piero; Krogvold, Lars; Jorgensen, Knut Dahl; Sebastiani, Guido; Dotta, Francesco
Reduced miR-184-3p expression protects pancreatic β-cells from lipotoxic and proinflammatory apoptosis in type 2 diabetes via CRTC1 upregulation
2022-01-01 Grieco, Giuseppina E; Brusco, Noemi; Fignani, Daniela; Nigi, Laura; Formichi, Caterina; Licata, Giada; Marselli, Lorella; Marchetti, Piero; Salvini, Laura; Tinti, Laura; Po, Agnese; Ferretti, Elisabetta; Sebastiani, Guido; Dotta, Francesco
Multi-Omics Integrative Approach of Extracellular Vesicles: A Future Challenging Milestone
2022-01-01 Shaba, Enxhi; Vantaggiato, Lorenza; Governini, Laura; Haxhiu, Alesandro; Sebastiani, Guido; Fignani, Daniela; Grieco, Giuseppina Emanuela; Bergantini, Laura; Bini, Luca; Landi, Claudia
MicroRNA circolanti come biomarcatori per il diabete mellito di tipo 2: avanzamenti e prospettive future
2022-01-01 Grieco, Giuseppina Emanuela; Fignani, Daniela; Dotta, Francesco; Sebastiani, Guido
The Landscape of microRNAs in βCell: between phenotype maintenance and protection
2021-01-01 Grieco, Giuseppina Emanuela; Brusco, Noemi; Licata, Giada; Fignani, Daniela; Formichi, Caterina; Nigi, Laura; Sebastiani, Guido; Dotta, Francesco
Protocol to analyze circulating small non-coding RNAs by high-throughput RNA sequencing from human plasma samples
2021-01-01 Grieco, G. E.; Sebastiani, G.; Fignani, D.; Brusco, N.; Nigi, L.; Formichi, C.; Licata, G.; Bruttini, M.; D'Aurizio, R.; Mathieu, C.; Gysemans, C.; Dotta, F.
Non-coding RNAs: novel players in insulin resistance and related diseases
2021-01-01 Formichi, Caterina; Nigi, Laura; Grieco, Giuseppina Emanuela; Maccora, Carla; Fignani, Daniela; Brusco, Noemi; Licata, Giada; Sebastiani, Guido; Dotta, Francesco
Circulating microRNAs signature for predicting response to GLP1-RA therapy in Type 2 diabetic patients: a pilot study
2021-01-01 Formichi, Caterina; Fignani, Daniela; Nigi, Laura; Grieco, Giuseppina Emanuela; Brusco, Noemi; Licata, Giada; Sabato, Claudia; Ferretti, Elisabetta; Sebastiani, Guido; Dotta, Francesco
Extracellular vesicles in immune system regulation and Type 1 diabetes: cell-to-cell communication Mediators, disease biomarkers, and promising therapeutic tools
2021-01-01 Grieco, G. E.; Fignani, D.; Formichi, C.; Nigi, L.; Licata, G.; Maccora, C.; Brusco, N.; Sebastiani, G.; Dotta, F.
MicroRNA expression in the aqueous humor of patients with diabetic macular edema
2020-01-01 Grieco, G. E.; Sebastiani, G.; Eandi, C. M.; Neri, G.; Nigi, L.; Brusco, N.; D'Aurizio, R.; Posarelli, M.; Bacci, T.; De Benedetto, E.; Fruschelli, M.; Orlandini, M.; Galvagni, F.; Dotta, F.; Tosi, G. M.
Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes
2020-01-01 Nigi, L.; Brusco, N.; Grieco, G. E.; Licata, G.; Krogvold, L.; Marselli, L.; Gysemans, C.; Overbergh, L.; Marchetti, P.; Mathieu, C.; Dahl Jorgensen, K.; Sebastiani, G.; Dotta, F.
SARS-CoV-2 receptor Angiotensin I-Converting Enzyme type 2 (ACE2) is expressed in human pancreatic β-cells and in the human pancreas microvasculature
2020-01-01 Fignani, D.; Licata, G.; Brusco, N.; Nigi, L.; Grieco, G. E.; Marselli, L.; Overbergh, L.; Gysemans, C.; Colli, M. L.; Marchetti, P.; Mathieu, C.; Eizirik, D. L.; Sebastiani, G.; Dotta, F.
Targeting microRNAs as a Therapeutic Strategy to Reduce Oxidative Stress in Diabetes
2019-01-01 Grieco, G. E.; Brusco, N.; Licata, G.; Nigi, L.; Formichi, C.; Dotta, F.; Sebastiani, G.
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Multi‐omics analysis reveals drivers of loss of β‐cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study | 1-gen-2024 | Armenteros, Jose Juan Almagro; Brorsson, Caroline; Johansen, Christian Holm; Banasik, Karina; Mazzoni, Gianluca; Moulder, Robert; Hirvonen, Karoliina; Suomi, Tomi; Rasool, Omid; Bruggraber, Sylvaine F. A.; Marcovecchio, M. Loredana; Hendricks, Emile; Al‐sari, Naba; Mattila, Ismo; Legido‐quigley, Cristina; Suvitaival, Tommi; Chmura, Piotr J.; Knip, Mikael; Schulte, Anke M.; Lee, Jeong Heon; Sebastiani, Guido; Grieco, Giuseppina Emanuela; Elo, Laura L.; Kaur, Simranjeet; Pociot, Flemming; Dotta, Francesco; Tree, Tim; Lahesmaa, Riitta; Overbergh, Lut; Mathieu, Chantal; Peakman, Mark; Brunak, Søren; Null, Null | - | |
| A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes | 1-gen-2024 | Sebastiani, Guido; Grieco, Giuseppina Emanuela; Bruttini, Marco; Auddino, Stefano; Mori, Alessia; Toniolli, Mattia; Fignani, Daniela; Licata, Giada; Aiello, Elena; Nigi, Laura; Formichi, Caterina; Fernandez-Tajes, Juan; Pugliese, Alberto; Evans-Molina, Carmella; Overbergh, Lut; Tree, Timothy; Peakman, Mark; Mathieu, Chantal; Dotta, Francesco | - | |
| A plasma miR-193b-365 signature combined with age and glycemic status predicts response to Lactococcus lactis-based antigen-specific immunotherapy in new-onset type 1 diabetes | 1-gen-2023 | Sassi, Gabriele; Licata, Giada; Ventriglia, Giuliana; Wouters, Amber; Lemaitre, Pierre; Seurinck, Ruth; Mori, Alessia; Grieco, Giuseppina Emanuela; Bissenova, Samal; Ellis, Darcy; Caluwaerts, Silvia; Rottiers, Pieter; Vandamme, Niels; Mathieu, Chantal; Dotta, Francesco; Gysemans, Conny; Sebastiani, Guido | - | |
| Intra-islet insulin synthesis defects are associated with endoplasmic reticulum stress and loss of beta cell identity in human diabetes | 1-gen-2023 | Brusco, Noemi; Sebastiani, Guido; Di Giuseppe, Gianfranco; Licata, Giada; Grieco, Giuseppina E; Fignani, Daniela; Nigi, Laura; Formichi, Caterina; Aiello, Elena; Auddino, Stefano; Quero, Giuseppe; Cefalo, Chiara M A; Cinti, Francesca; Mari, Andrea; Ferraro, Pietro M; Pontecorvi, Alfredo; Alfieri, Sergio; Giaccari, Andrea; Dotta, Francesco; Mezza, Teresa | - | |
| Angiotensin I-converting enzyme type 2 expression is increased in pancreatic islets of type 2 diabetic donors | 1-gen-2023 | Fignani, Daniela; Pedace, Erika; Licata, Giada; Grieco, Giuseppina Emanuela; Aiello, Elena; de Luca, Carmela; Marselli, Lorella; Marchetti, Piero; Sebastiani, Guido; Dotta, Francesco | - | |
| Identification and Validation of miR-222-3p and miR-409-3p as Plasma Biomarkers in Gestational Diabetes Mellitus Sharing Validated Target Genes Involved in Metabolic Homeostasis | 1-gen-2022 | Filardi, Tiziana; Catanzaro, Giuseppina; Grieco, Giuseppina Emanuela; Splendiani, Elena; Trocchianesi, Sofia; Santangelo, Carmela; Brunelli, Roberto; Guarino, Elisa; Sebastiani, Guido; Dotta, Francesco; Morano, Susanna; Ferretti, Elisabetta | - | |
| Circulating microRNAs as clinically useful biomarkers for Type 2 Diabetes Mellitus: miRNomics from bench to bedside | 1-gen-2022 | Grieco, Giuseppina Emanuela; Besharat, Zein Mersini; Licata, Giada; Fignani, Daniela; Brusco, Noemi; Nigi, Laura; Formichi, Caterina; Po, Agnese; Sabato, Claudia; Dardano, Angela; Natali, Andrea; Dotta, Francesco; Sebastiani, Guido; Ferretti, Elisabetta | - | |
| Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors | 1-gen-2022 | Nigi, Laura; Brusco, Noemi; Grieco, Giuseppina E; Fignani, Daniela; Licata, Giada; Formichi, Caterina; Aiello, Elena; Marselli, Lorella; Marchetti, Piero; Krogvold, Lars; Jorgensen, Knut Dahl; Sebastiani, Guido; Dotta, Francesco | - | |
| Reduced miR-184-3p expression protects pancreatic β-cells from lipotoxic and proinflammatory apoptosis in type 2 diabetes via CRTC1 upregulation | 1-gen-2022 | Grieco, Giuseppina E; Brusco, Noemi; Fignani, Daniela; Nigi, Laura; Formichi, Caterina; Licata, Giada; Marselli, Lorella; Marchetti, Piero; Salvini, Laura; Tinti, Laura; Po, Agnese; Ferretti, Elisabetta; Sebastiani, Guido; Dotta, Francesco | - | |
| Multi-Omics Integrative Approach of Extracellular Vesicles: A Future Challenging Milestone | 1-gen-2022 | Shaba, Enxhi; Vantaggiato, Lorenza; Governini, Laura; Haxhiu, Alesandro; Sebastiani, Guido; Fignani, Daniela; Grieco, Giuseppina Emanuela; Bergantini, Laura; Bini, Luca; Landi, Claudia | - | |
| MicroRNA circolanti come biomarcatori per il diabete mellito di tipo 2: avanzamenti e prospettive future | 1-gen-2022 | Grieco, Giuseppina Emanuela; Fignani, Daniela; Dotta, Francesco; Sebastiani, Guido | - | |
| The Landscape of microRNAs in βCell: between phenotype maintenance and protection | 1-gen-2021 | Grieco, Giuseppina Emanuela; Brusco, Noemi; Licata, Giada; Fignani, Daniela; Formichi, Caterina; Nigi, Laura; Sebastiani, Guido; Dotta, Francesco | - | |
| Protocol to analyze circulating small non-coding RNAs by high-throughput RNA sequencing from human plasma samples | 1-gen-2021 | Grieco, G. E.; Sebastiani, G.; Fignani, D.; Brusco, N.; Nigi, L.; Formichi, C.; Licata, G.; Bruttini, M.; D'Aurizio, R.; Mathieu, C.; Gysemans, C.; Dotta, F. | - | |
| Non-coding RNAs: novel players in insulin resistance and related diseases | 1-gen-2021 | Formichi, Caterina; Nigi, Laura; Grieco, Giuseppina Emanuela; Maccora, Carla; Fignani, Daniela; Brusco, Noemi; Licata, Giada; Sebastiani, Guido; Dotta, Francesco | - | |
| Circulating microRNAs signature for predicting response to GLP1-RA therapy in Type 2 diabetic patients: a pilot study | 1-gen-2021 | Formichi, Caterina; Fignani, Daniela; Nigi, Laura; Grieco, Giuseppina Emanuela; Brusco, Noemi; Licata, Giada; Sabato, Claudia; Ferretti, Elisabetta; Sebastiani, Guido; Dotta, Francesco | - | |
| Extracellular vesicles in immune system regulation and Type 1 diabetes: cell-to-cell communication Mediators, disease biomarkers, and promising therapeutic tools | 1-gen-2021 | Grieco, G. E.; Fignani, D.; Formichi, C.; Nigi, L.; Licata, G.; Maccora, C.; Brusco, N.; Sebastiani, G.; Dotta, F. | - | |
| MicroRNA expression in the aqueous humor of patients with diabetic macular edema | 1-gen-2020 | Grieco, G. E.; Sebastiani, G.; Eandi, C. M.; Neri, G.; Nigi, L.; Brusco, N.; D'Aurizio, R.; Posarelli, M.; Bacci, T.; De Benedetto, E.; Fruschelli, M.; Orlandini, M.; Galvagni, F.; Dotta, F.; Tosi, G. M. | - | |
| Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes | 1-gen-2020 | Nigi, L.; Brusco, N.; Grieco, G. E.; Licata, G.; Krogvold, L.; Marselli, L.; Gysemans, C.; Overbergh, L.; Marchetti, P.; Mathieu, C.; Dahl Jorgensen, K.; Sebastiani, G.; Dotta, F. | - | |
| SARS-CoV-2 receptor Angiotensin I-Converting Enzyme type 2 (ACE2) is expressed in human pancreatic β-cells and in the human pancreas microvasculature | 1-gen-2020 | Fignani, D.; Licata, G.; Brusco, N.; Nigi, L.; Grieco, G. E.; Marselli, L.; Overbergh, L.; Gysemans, C.; Colli, M. L.; Marchetti, P.; Mathieu, C.; Eizirik, D. L.; Sebastiani, G.; Dotta, F. | - | |
| Targeting microRNAs as a Therapeutic Strategy to Reduce Oxidative Stress in Diabetes | 1-gen-2019 | Grieco, G. E.; Brusco, N.; Licata, G.; Nigi, L.; Formichi, C.; Dotta, F.; Sebastiani, G. | - |
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