Sfoglia per Rivista ACS MEDICINAL CHEMISTRY LETTERS
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein
2020-01-01 Malancona, Savina; Mori, Mattia; Fezzardi, Paola; Santoriello, Marisabella; Basta, Andreina; Nibbio, Martina; Kovalenko, Lesia; Speziale, Roberto; Battista, Maria Rosaria; Cellucci, Antonella; Gennari, Nadia; Monteagudo, Edith; Di Marco, Annalise; Giannini, Alessia; Sharma, Rajhans; Pires, Manuel; Real, Eleonore; Zazzi, Maurizio; Dasso Lang, Maria Chiara; De Forni, Davide; Saladini, Francesco; Mely, Yves; Summa, Vincenzo; Harper, Steven; Botta, Maurizio
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders
2019-01-01 Brogi, Simone; Campiani, Giuseppe; Brindisi, Margherita; Butini, Stefania
AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma
2020-01-01 Molinari, Alessio; Iovenitti, Giulia; Mancini, Arianna; Luca Gravina, Giovanni; Chebbi, Monia; Caruana, Maura; Vignaroli, Giulia; Orofino, Francesco; Rango, Enrico; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Botta, Maurizio
Bivalent Ligands for the Serotonin 5-HT3 Receptor
2011-01-01 Cappelli, Andrea; Manini, Monica; Paolino, Marco; Gallelli, Andrea; Anzini, Maurizio; Mennuni, Laura; Del Cadia, Marta; De Rienzo, Francesca; Menziani, M. Cristina; Vomero, Salvatore
Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia
2019-01-01 Quaglio, D.; Zhdanovskaya, N.; Tobajas, G.; Cuartas, V.; Balducci, S.; Christodoulou, M. S.; Fabrizi, G.; Gargantilla, M.; Priego, E. -M.; Carmona Pestania, A.; Passarella, D.; Screpanti, I.; Botta, B.; Palermo, R.; Mori, M.; Ghirga, F.; Perez-Perez, M. -J.
A Class of Potent Inhibitors of the HIV-1 Nucleocapsid Protein Based on Aminopyrrolic Scaffolds
2020-01-01 Ciaco, S.; Humbert, N.; Real, E.; Boudier, C.; Francesconi, O.; Roelens, S.; Nativi, C.; Seguin-Devaux, C.; Mori, M.; Mely, Y.
Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors
2023-01-01 Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena
Discovery of 1,4-Naphthoquinones as a New Class of Antiproliferative Agents Targeting GPR55
2019-01-01 Badolato, Mariateresa; Carullo, Gabriele; Caroleo, Maria Cristina; Cione, Erika; Aiello, Francesca; Manetti, Fabrizio
Discovery of a New Class of Potent MMP Inhibitors by Structure-Based Optimization of the Arylsulfonamide Scaffold
2013-01-01 Mori, Mattia; Massaro, Assunta; Calderone, Vito; Fragai, Marco; Luchinat, Claudio; Mordini, Alessandro
Exploring oxidovanadium(IV) complexes as YopH inhibitors: mechanism of action and modeling studies
2015-01-01 Martins, Priscila G. A; Mori, Mattia; Chiaradia Delatorre, Louise D; Menegatti, Angela C. O; Mascarello, Alessandra; Botta, Bruno; Benítez, Julio; Gambino, Dinorah; Terenzi, Hernán
Exploring the implication of DDX3X in DENV infection: discovery of the first-in-class DDX3X fluorescent inhibitor
2020-01-01 Brai, Annalaura; Boccuto, Adele; Monti, Martina; Marchi, Serena; Vicenti, Ilaria; Saladini, Francesco; Trivisani, CLAUDIA IMMACOLATA; Pollutri, Alessandro; Trombetta, CLAUDIA MARIA; Montomoli, Emanuele; Riva, Valentina; Garbelli, Anna; Maria Nola, Emanuele; Zazzi, Maurizio; Maga, Giovanni; Dreassi, Elena; Botta, Maurizio
From Taxuspine X to structurally simplified Taxanes with remarkable P-Glycoprotein inhibitory activity
2010-01-01 Castagnolo, Daniele; Contemori, Lorenzo; Maccari, Giorgio; S. I., Avramova; Neri, Alessandro; Sgaragli, GIAN PIETRO; Botta, Maurizio
Improving the Potency of N-Aryl-2,5-dimethylpyrroles against Multidrug-Resistant and Intracellular Mycobacteria
2020-01-01 Touitou, M.; Manetti, F.; Ribeiro, C. M.; Pavan, F. R.; Scalacci, N.; Zrebna, K.; Begum, N.; Semenya, D.; Gupta, A.; Bhakta, S.; Mchugh, T. D.; Senderowitz, H.; Kyriazi, M.; Castagnolo, D.
In Memory of Maurizio Botta: His Vision of Medicinal Chemistry
2020-01-01 Botta, Lorenzo; Mori, Mattia
Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA
2012-01-01 Brincat, Jp; Broccatelli, F; Sabatini, S; Frosini, Maria; Neri, Annalisa; Kaatz, Gw; Cruciani, G; Carosati, E.
Multifunctional Cholinesterase and Amyloid Beta Fibrillization Modulators. Synthesis and Biological Investigation
2013-01-01 Butini, Stefania; Brindisi, Margherita; Brogi, Simone; Maramai, Samuele; Egeria, Guarino; Alessandro, Panico; Ashima, Saxena; Ved, Chauhan; Raffaella, Colombo; Laura, Verga; Ersilia De, Lorenzi; Manuela, Bartolini; Vincenza, Andrisano; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra
New frontiers in kinases: special issue
2014-01-01 Botta, Maurizio
Novel Macrocyclic Amidinoureas: Potent Non-Azole Antifungals Active against Wild-Type and Resistant Candida Species
2013-01-01 Sanguinetti, M.; Sanfilippo, S.; Castagnolo, Daniele; Sanglard, D.; Posteraro, B.; Donzellini, G.; Botta, Maurizio
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists
2020-01-01 Pasquinucci, Lorella; Parenti, Carmela; Ruiz-Cantero M., Carmen; Georgoussi, Zafiroula; Pallaki, Paschalina; Cobos J., Enrique; Amata, Emanuele; Marrazzo, Agostino; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Salerno, Loredana; Turnaturi, Rita
Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents
2020-01-01 Manetti, Fabrizio; Stecca, Barbara; Santini, Roberta; Maresca, Luisa; Giannini, Giuseppe; Taddei, Maurizio; Petricci, Elena
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein | 1-gen-2020 | Malancona, Savina; Mori, Mattia; Fezzardi, Paola; Santoriello, Marisabella; Basta, Andreina; Nibbio, Martina; Kovalenko, Lesia; Speziale, Roberto; Battista, Maria Rosaria; Cellucci, Antonella; Gennari, Nadia; Monteagudo, Edith; Di Marco, Annalise; Giannini, Alessia; Sharma, Rajhans; Pires, Manuel; Real, Eleonore; Zazzi, Maurizio; Dasso Lang, Maria Chiara; De Forni, Davide; Saladini, Francesco; Mely, Yves; Summa, Vincenzo; Harper, Steven; Botta, Maurizio | - | |
| Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders | 1-gen-2019 | Brogi, Simone; Campiani, Giuseppe; Brindisi, Margherita; Butini, Stefania | - | |
| AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma | 1-gen-2020 | Molinari, Alessio; Iovenitti, Giulia; Mancini, Arianna; Luca Gravina, Giovanni; Chebbi, Monia; Caruana, Maura; Vignaroli, Giulia; Orofino, Francesco; Rango, Enrico; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Botta, Maurizio | - | |
| Bivalent Ligands for the Serotonin 5-HT3 Receptor | 1-gen-2011 | Cappelli, Andrea; Manini, Monica; Paolino, Marco; Gallelli, Andrea; Anzini, Maurizio; Mennuni, Laura; Del Cadia, Marta; De Rienzo, Francesca; Menziani, M. Cristina; Vomero, Salvatore | - | |
| Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia | 1-gen-2019 | Quaglio, D.; Zhdanovskaya, N.; Tobajas, G.; Cuartas, V.; Balducci, S.; Christodoulou, M. S.; Fabrizi, G.; Gargantilla, M.; Priego, E. -M.; Carmona Pestania, A.; Passarella, D.; Screpanti, I.; Botta, B.; Palermo, R.; Mori, M.; Ghirga, F.; Perez-Perez, M. -J. | - | |
| A Class of Potent Inhibitors of the HIV-1 Nucleocapsid Protein Based on Aminopyrrolic Scaffolds | 1-gen-2020 | Ciaco, S.; Humbert, N.; Real, E.; Boudier, C.; Francesconi, O.; Roelens, S.; Nativi, C.; Seguin-Devaux, C.; Mori, M.; Mely, Y. | - | |
| Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors | 1-gen-2023 | Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena | - | |
| Discovery of 1,4-Naphthoquinones as a New Class of Antiproliferative Agents Targeting GPR55 | 1-gen-2019 | Badolato, Mariateresa; Carullo, Gabriele; Caroleo, Maria Cristina; Cione, Erika; Aiello, Francesca; Manetti, Fabrizio | - | |
| Discovery of a New Class of Potent MMP Inhibitors by Structure-Based Optimization of the Arylsulfonamide Scaffold | 1-gen-2013 | Mori, Mattia; Massaro, Assunta; Calderone, Vito; Fragai, Marco; Luchinat, Claudio; Mordini, Alessandro | - | |
| Exploring oxidovanadium(IV) complexes as YopH inhibitors: mechanism of action and modeling studies | 1-gen-2015 | Martins, Priscila G. A; Mori, Mattia; Chiaradia Delatorre, Louise D; Menegatti, Angela C. O; Mascarello, Alessandra; Botta, Bruno; Benítez, Julio; Gambino, Dinorah; Terenzi, Hernán | - | |
| Exploring the implication of DDX3X in DENV infection: discovery of the first-in-class DDX3X fluorescent inhibitor | 1-gen-2020 | Brai, Annalaura; Boccuto, Adele; Monti, Martina; Marchi, Serena; Vicenti, Ilaria; Saladini, Francesco; Trivisani, CLAUDIA IMMACOLATA; Pollutri, Alessandro; Trombetta, CLAUDIA MARIA; Montomoli, Emanuele; Riva, Valentina; Garbelli, Anna; Maria Nola, Emanuele; Zazzi, Maurizio; Maga, Giovanni; Dreassi, Elena; Botta, Maurizio | - | |
| From Taxuspine X to structurally simplified Taxanes with remarkable P-Glycoprotein inhibitory activity | 1-gen-2010 | Castagnolo, Daniele; Contemori, Lorenzo; Maccari, Giorgio; S. I., Avramova; Neri, Alessandro; Sgaragli, GIAN PIETRO; Botta, Maurizio | - | |
| Improving the Potency of N-Aryl-2,5-dimethylpyrroles against Multidrug-Resistant and Intracellular Mycobacteria | 1-gen-2020 | Touitou, M.; Manetti, F.; Ribeiro, C. M.; Pavan, F. R.; Scalacci, N.; Zrebna, K.; Begum, N.; Semenya, D.; Gupta, A.; Bhakta, S.; Mchugh, T. D.; Senderowitz, H.; Kyriazi, M.; Castagnolo, D. | - | |
| In Memory of Maurizio Botta: His Vision of Medicinal Chemistry | 1-gen-2020 | Botta, Lorenzo; Mori, Mattia | - | |
| Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA | 1-gen-2012 | Brincat, Jp; Broccatelli, F; Sabatini, S; Frosini, Maria; Neri, Annalisa; Kaatz, Gw; Cruciani, G; Carosati, E. | - | |
| Multifunctional Cholinesterase and Amyloid Beta Fibrillization Modulators. Synthesis and Biological Investigation | 1-gen-2013 | Butini, Stefania; Brindisi, Margherita; Brogi, Simone; Maramai, Samuele; Egeria, Guarino; Alessandro, Panico; Ashima, Saxena; Ved, Chauhan; Raffaella, Colombo; Laura, Verga; Ersilia De, Lorenzi; Manuela, Bartolini; Vincenza, Andrisano; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra | - | |
| New frontiers in kinases: special issue | 1-gen-2014 | Botta, Maurizio | - | |
| Novel Macrocyclic Amidinoureas: Potent Non-Azole Antifungals Active against Wild-Type and Resistant Candida Species | 1-gen-2013 | Sanguinetti, M.; Sanfilippo, S.; Castagnolo, Daniele; Sanglard, D.; Posteraro, B.; Donzellini, G.; Botta, Maurizio | - | |
| Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists | 1-gen-2020 | Pasquinucci, Lorella; Parenti, Carmela; Ruiz-Cantero M., Carmen; Georgoussi, Zafiroula; Pallaki, Paschalina; Cobos J., Enrique; Amata, Emanuele; Marrazzo, Agostino; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Salerno, Loredana; Turnaturi, Rita | - | |
| Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents | 1-gen-2020 | Manetti, Fabrizio; Stecca, Barbara; Santini, Roberta; Maresca, Luisa; Giannini, Giuseppe; Taddei, Maurizio; Petricci, Elena | - |
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