Articular cartilage (AC), a highly specialised tissue that provides low friction and allows for efficient load bearing and distribution, can undergo disruption for traumatic or degenerative processes. Conservative treatment with various medications gives only temporary relief of symptoms rather than cure. Since 1960 several surgical procedures have been tested without significant improvement of AC regeneration. Actually, third generation tissue engineering applied to the cartilage tissue regeneration is giving promising results. The right combination of cell types, scaffolds and culture media can represent the only way to cure degenerated cartilage tissue. However, several critical issues need to be overcome.
Leone, G. (2011). Cartilage replacement implants using hydrogels. In Biomedical hydrogelsBiochemistry, manufacture andmedical applications (pp. 149-183). CAMBRIDGE : Woodhead Publishing Limited, Ed Steve Rimmer [10.1016/B978-1-84569-590-3.50008-4].
Cartilage replacement implants using hydrogels
Leone, Gemma
2011-01-01
Abstract
Articular cartilage (AC), a highly specialised tissue that provides low friction and allows for efficient load bearing and distribution, can undergo disruption for traumatic or degenerative processes. Conservative treatment with various medications gives only temporary relief of symptoms rather than cure. Since 1960 several surgical procedures have been tested without significant improvement of AC regeneration. Actually, third generation tissue engineering applied to the cartilage tissue regeneration is giving promising results. The right combination of cell types, scaffolds and culture media can represent the only way to cure degenerated cartilage tissue. However, several critical issues need to be overcome.
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https://hdl.handle.net/11365/425632
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