Abstract Objective: To evaluate the pregnancy outcome in women >30 years old with uterine fibroids also considering other possible concomitant risk factors. Methods: A multicentric, observational and retrospective study was conducted. All women were asked to complete a questionnaire while they were in hospital and the outcome of pregnancy was investigated. Results: Women with uterine fibroids before pregnancy were more frequently >35 years old and in their clinical history before pregnancy showed more pelvic pain, polliachiuria, previous pelvic surgery, hypermenorrhea and dysmenorrhea, than control women (P<0.0001). During pregnancy patients with uterine fibroids showed significantly more threatened preterm birth and preterm birth, weight gain, hyperemesis, gestational hypertension and post partum bleeding and showed more often requirement for emergency cesarean section (P<0.0001). The multivariate logistic regression model used for evaluating the effect of clinical parameters on outcome of pregnancy showed that age > 35 years, pelvic pain, work, weight gain, hyperemesis, threatened miscarriage and threatened preterm birth were significantly correlated with unfavorable pregnancy outcome, independently of the presence of uterine fibroids (P<0.0001). Conclusions: The present study confirming a more frequent negative pregnancy outcome in presence of uterine fibroids, showed that other risk factors may affect pregnancy and delivery outcome in women aging > 30 years old.
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|Titolo:||Uterine fibroids affect pregnancy outcome in women over 30 years old: role of other risk factors.|
|Citazione:||Conti, N., Tosti, C., Pinzauti, S., Tomaiuolo, T., Cevenini, G., Severi, F.M., et al. (2012). Uterine fibroids affect pregnancy outcome in women over 30 years old: role of other risk factors. THE JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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