In the medfly Ceratitis capitata the female accessory glands secrete a fluid containing several proteins, most of them of low molecular weight. Such fluid was found to have antimicrobial properties, including lysozyme activity. Two closely related 3 kDa peptides, named ceratotoxins A and B, effective against E. coli K12, were purified from the secretion. Synthetic ceratotoxin A was tested and demonstrated effective against several Gram-negative and -positive bacterial strains. The cDNA sequence encoding ceratotoxin A was determined. Ceratotoxin gene resulted to be sex-specific and expressed exclusively in the accessory glands of the female adult of Ceratitis capitata.

Marchini, D., Marri, L., M., R., A. G. O., M., C., B., J., T., et al. (1994). Ceratotoxin: antimicrobial activity of the peptide and expression of the gene. In VI International Colloquium on Invertebrate Pathology and Microbial Control - Proceedings (pp. 460-463). GANGES : Society for Invertebrate Pathology, 1994. Montpellier, France. Societé Viganaise d'Imprimerie.

Ceratotoxin: antimicrobial activity of the peptide and expression of the gene

MARCHINI, DANIELA;MARRI, LAURA;
1994

Abstract

In the medfly Ceratitis capitata the female accessory glands secrete a fluid containing several proteins, most of them of low molecular weight. Such fluid was found to have antimicrobial properties, including lysozyme activity. Two closely related 3 kDa peptides, named ceratotoxins A and B, effective against E. coli K12, were purified from the secretion. Synthetic ceratotoxin A was tested and demonstrated effective against several Gram-negative and -positive bacterial strains. The cDNA sequence encoding ceratotoxin A was determined. Ceratotoxin gene resulted to be sex-specific and expressed exclusively in the accessory glands of the female adult of Ceratitis capitata.
Marchini, D., Marri, L., M., R., A. G. O., M., C., B., J., T., et al. (1994). Ceratotoxin: antimicrobial activity of the peptide and expression of the gene. In VI International Colloquium on Invertebrate Pathology and Microbial Control - Proceedings (pp. 460-463). GANGES : Society for Invertebrate Pathology, 1994. Montpellier, France. Societé Viganaise d'Imprimerie.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/37867
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