Imaging of upper GI malignancy plays a key role in addressing patient management. The introduction of multimodal therapy opened new pathways to treat once unresectable patients, requiring high accuracy from imaging to define specific treatment. Even if magnetic Resonance Imaging (MRI) gains ground, Computed Tomography (CT) remains the gold-standard imaging technique since it allows the evaluation of T, N and M parameters with a single, cost-effective, examination. Locoregional staging can be supported by EUS which allows a better definition of parietal layers. Nodal staging remains a critical open issue since no one imaging technique can define certain pathological nodes when small in dimension. Distant metastases can be individuated by CT and confirmed with the aid of MRI (liver, brain) or video laparoscopy (peritoneum). The knowledge of the natural history of neoplasms, together with the correctness of the exam methodology, is crucial to define the burden of the disease and address the patient to specific care pathways.
Mazzei, M.A., Di Meglio, N., Gentili, F., Bagnacci, G., Macchiarelli, R., Volterrani, L. (2023). Upper GI tract. In E. Neri, P. A. Erba (a cura di), Multimodality Imaging and Intervention in Oncology (pp. 227-233). Springer Cham [10.1007/978-3-031-28524-0_11].
Upper GI tract
Mazzei M. A.;Di Meglio N.;Gentili F.;Bagnacci G.;Macchiarelli R.;Volterrani L.
2023-01-01
Abstract
Imaging of upper GI malignancy plays a key role in addressing patient management. The introduction of multimodal therapy opened new pathways to treat once unresectable patients, requiring high accuracy from imaging to define specific treatment. Even if magnetic Resonance Imaging (MRI) gains ground, Computed Tomography (CT) remains the gold-standard imaging technique since it allows the evaluation of T, N and M parameters with a single, cost-effective, examination. Locoregional staging can be supported by EUS which allows a better definition of parietal layers. Nodal staging remains a critical open issue since no one imaging technique can define certain pathological nodes when small in dimension. Distant metastases can be individuated by CT and confirmed with the aid of MRI (liver, brain) or video laparoscopy (peritoneum). The knowledge of the natural history of neoplasms, together with the correctness of the exam methodology, is crucial to define the burden of the disease and address the patient to specific care pathways.
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https://hdl.handle.net/11365/1266435