Primary cellular immunodeficiencies may often initially present with manifestations affecting the gastrointestinal tract. Not only infections but also inflammatory, autoimmune, and in some cases malignant manifestations may suggest the presence of a defect in the immune system. Gastrointestinal manifestations are present in 5–50% of patients with primary immunodeficiency, which is not surprising since the intestine is the largest lymphoid organ.
Troilo, A., Frede, N., Della Bella, C., D'Elios, M.M. (2021). Gut Involvement in Cellular Immunodeficiencies. In Cellular Primary Immunodeficiencies, Rare Diseases of the Immune System (pp. 343-360). Berlin : Springer [10.1007/978-3-030-70107-9_13].
Gut Involvement in Cellular Immunodeficiencies
D'Elios, M. M.
2021-01-01
Abstract
Primary cellular immunodeficiencies may often initially present with manifestations affecting the gastrointestinal tract. Not only infections but also inflammatory, autoimmune, and in some cases malignant manifestations may suggest the presence of a defect in the immune system. Gastrointestinal manifestations are present in 5–50% of patients with primary immunodeficiency, which is not surprising since the intestine is the largest lymphoid organ.
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https://hdl.handle.net/11365/1220572