In this chapter, a brief overview of fundamentals in mass spectrometry and some applications are presented. The main concepts in ionization techniques, classical techniques and ambient mass spectrometry are followed by an overview on analyzers. Particular attention has been paid to high resolution mass spectrometry and accurate mass measurements, highly debating topics in modern mass spectrometry, with some examples and applications. Finally tandem mass spectrometry, collision-induced dissociations (CID), interactions of ions with electrons (ECD, ETD), photons (IRMPD) and with surfaces (SID) are also briefly presented.
Giorgi, G. (2017). Mass Spectrometry and High Resolution Mass Spectrometry: An Overview. In R.M.C. J. H. Banoub (a cura di), Molecular Technologies for Detection of Chemical and Biological Agents (pp. 89-101). Springer [10.1007/978-94-024-1113-3_5].
Mass Spectrometry and High Resolution Mass Spectrometry: An Overview
GIORGI, GIANLUCA
2017-01-01
Abstract
In this chapter, a brief overview of fundamentals in mass spectrometry and some applications are presented. The main concepts in ionization techniques, classical techniques and ambient mass spectrometry are followed by an overview on analyzers. Particular attention has been paid to high resolution mass spectrometry and accurate mass measurements, highly debating topics in modern mass spectrometry, with some examples and applications. Finally tandem mass spectrometry, collision-induced dissociations (CID), interactions of ions with electrons (ECD, ETD), photons (IRMPD) and with surfaces (SID) are also briefly presented.
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https://hdl.handle.net/11365/1012556
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