Optical coherence tomography (OCT) is the most sensitive and promising diagnostic technique for detecting damage to optic nerve fibres. OCT is a modern imaging technique based on analysis of semicoherent radiation reflected by the structure of the tissue analysed. The high resolution possible with OCT (about 2–5 μm versus 150 μm with ultrasonometry) enables noninvasive imaging of the anterior chamber, retinal layers, choriocapillaris, retinal pigmented epithelium (RPE) and optic nerve/lamina cribrosa. In glaucoma, OCT-derived structural parameters such as retinal nerve fibre layer (RNFL) and macular ganglion cell complex thicknesses are widely used for early glaucoma detection and assessing glaucoma progression; in addition, OCT image of the anterior chamber is of special interest for assessing the amplitude and conformation of the angle, complementing gonioscopic evaluation. In this chapter, we consider the information that OCT offers for studying, classifying and monitoring glaucoma patients through: anterior pole evaluation, retinal nerve fibre layer and optic nerve head analysis, ganglion cell analysis and lamina cribrosa assessment.
Frezzotti, P. (2016). Optical Coherence Tomography. In Antonio Ferreras (a cura di), Glaucoma Imaging (pp. 227-263). Springer International Publishing [10.1007/978-3-319-18959-8_9].
Optical Coherence Tomography
FREZZOTTI, PAOLO
2016-01-01
Abstract
Optical coherence tomography (OCT) is the most sensitive and promising diagnostic technique for detecting damage to optic nerve fibres. OCT is a modern imaging technique based on analysis of semicoherent radiation reflected by the structure of the tissue analysed. The high resolution possible with OCT (about 2–5 μm versus 150 μm with ultrasonometry) enables noninvasive imaging of the anterior chamber, retinal layers, choriocapillaris, retinal pigmented epithelium (RPE) and optic nerve/lamina cribrosa. In glaucoma, OCT-derived structural parameters such as retinal nerve fibre layer (RNFL) and macular ganglion cell complex thicknesses are widely used for early glaucoma detection and assessing glaucoma progression; in addition, OCT image of the anterior chamber is of special interest for assessing the amplitude and conformation of the angle, complementing gonioscopic evaluation. In this chapter, we consider the information that OCT offers for studying, classifying and monitoring glaucoma patients through: anterior pole evaluation, retinal nerve fibre layer and optic nerve head analysis, ganglion cell analysis and lamina cribrosa assessment.
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https://hdl.handle.net/11365/1002440