TRUGLIO, GIUSEPPINA IVANA
TRUGLIO, GIUSEPPINA IVANA
Dipartimento di Biotecnologie, Chimica e Farmacia
A gram-scale synthesis of a macrocyclic amidinourea with strong antifungal activity through a Fukuyama tri-protected polyamine intermediate
2019-01-01 Borgini, Matteo; Orofino, Francesco; Truglio, Giuseppina I.; Balestri, Lorenzo; Botta, Maurizio
Alkyl-guanidine Compounds as Potent Broad-Spectrum Antibacterial Agents: Chemical Library Extension and Biological Characterization
2018-01-01 Pasero, Carolina; D'Agostino, Ilaria; De Luca, Filomena; Zamperini, Claudio; Deodato, Davide; Truglio, Giuseppina I.; Sannio, Filomena; DEL PRETE, Rosita; Ferraro, Teresa; Visaggio, Daniela; Mancini, Arianna; Guglielmi, Mario B.; Visca, Paolo; Docquier, Jean-Denis; Botta, Maurizio
CanB, a druggable cellular target in mycobacterium tuberculosis
2023-01-01 Degiacomi, G; Gianibbi, B; Recchia, D; Stelitano, G; Truglio, Gi; Marra, P; Stamilla, A; Makarov, V; Chiarelli, Lr; Manetti, F; Pasca, Mr
Design and synthesis of a novel inhibitor of T. Viride chitinase through an in silico target fishing protocol
2017-01-01 Maccari, Giorgio; Deodato, Davide; Fiorucci, Diego; Orofino, Francesco; Truglio, Giuseppina I.; Pasero, Carolina; Martini, Riccardo; De Luca, Filomena; Docquier, Jean-Denis; Botta, Maurizio
Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors
2023-01-01 Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena
Focused library of phenyl-fused macrocyclic amidinoureas as antifungal agents
2022-01-01 Balestri, Lorenzo J. I.; D’Agostino, Ilaria; Rango, Enrico; Vagaggini, Chiara; Marchitiello, Rosalba; Mariotti, Melinda; Casian, Alexandru; Deodato, Davide; Truglio, Giuseppina I.; Orofino, Francesco; Sanguinetti, Maurizio; Bugli, Francesca; Botta, Lorenzo; Dreassi, Elena
In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains
2020-01-01 Orofino, F.; Truglio, G. I.; Fiorucci, D.; D'Agostino, I.; Borgini, M.; Poggialini, F.; Zamperini, C.; Dreassi, E.; Maccari, L.; Torelli, R.; Martini, C.; Bernabei, M.; Meis, J. F.; Khandelwal, N. K.; Prasad, R.; Sanguinetti, M.; Bugli, F.; Botta, M.
Ruthenium-catalysed C-alkylation of 1,3-dicarbonyl compounds with primary alcohols and synthesis of 3-keto-quinolines
2016-01-01 Cini, Elena; Petricci, Elena; Truglio, GIUSEPPINA IVANA; Vecchio, Marialaura; Taddei, Maurizio
Synthesis and biological evaluation of hAMCase inhibitors and anomeric equilibrium of gluco and xylopyranose derivatives in D2O
2019-01-01 Truglio, G
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A gram-scale synthesis of a macrocyclic amidinourea with strong antifungal activity through a Fukuyama tri-protected polyamine intermediate | 1-gen-2019 | Borgini, Matteo; Orofino, Francesco; Truglio, Giuseppina I.; Balestri, Lorenzo; Botta, Maurizio | - | |
| Alkyl-guanidine Compounds as Potent Broad-Spectrum Antibacterial Agents: Chemical Library Extension and Biological Characterization | 1-gen-2018 | Pasero, Carolina; D'Agostino, Ilaria; De Luca, Filomena; Zamperini, Claudio; Deodato, Davide; Truglio, Giuseppina I.; Sannio, Filomena; DEL PRETE, Rosita; Ferraro, Teresa; Visaggio, Daniela; Mancini, Arianna; Guglielmi, Mario B.; Visca, Paolo; Docquier, Jean-Denis; Botta, Maurizio | - | |
| CanB, a druggable cellular target in mycobacterium tuberculosis | 1-gen-2023 | Degiacomi, G; Gianibbi, B; Recchia, D; Stelitano, G; Truglio, Gi; Marra, P; Stamilla, A; Makarov, V; Chiarelli, Lr; Manetti, F; Pasca, Mr | - | |
| Design and synthesis of a novel inhibitor of T. Viride chitinase through an in silico target fishing protocol | 1-gen-2017 | Maccari, Giorgio; Deodato, Davide; Fiorucci, Diego; Orofino, Francesco; Truglio, Giuseppina I.; Pasero, Carolina; Martini, Riccardo; De Luca, Filomena; Docquier, Jean-Denis; Botta, Maurizio | - | |
| Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors | 1-gen-2023 | Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena | - | |
| Focused library of phenyl-fused macrocyclic amidinoureas as antifungal agents | 1-gen-2022 | Balestri, Lorenzo J. I.; D’Agostino, Ilaria; Rango, Enrico; Vagaggini, Chiara; Marchitiello, Rosalba; Mariotti, Melinda; Casian, Alexandru; Deodato, Davide; Truglio, Giuseppina I.; Orofino, Francesco; Sanguinetti, Maurizio; Bugli, Francesca; Botta, Lorenzo; Dreassi, Elena | - | |
| In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains | 1-gen-2020 | Orofino, F.; Truglio, G. I.; Fiorucci, D.; D'Agostino, I.; Borgini, M.; Poggialini, F.; Zamperini, C.; Dreassi, E.; Maccari, L.; Torelli, R.; Martini, C.; Bernabei, M.; Meis, J. F.; Khandelwal, N. K.; Prasad, R.; Sanguinetti, M.; Bugli, F.; Botta, M. | - | |
| Ruthenium-catalysed C-alkylation of 1,3-dicarbonyl compounds with primary alcohols and synthesis of 3-keto-quinolines | 1-gen-2016 | Cini, Elena; Petricci, Elena; Truglio, GIUSEPPINA IVANA; Vecchio, Marialaura; Taddei, Maurizio | - | |
| Synthesis and biological evaluation of hAMCase inhibitors and anomeric equilibrium of gluco and xylopyranose derivatives in D2O | 1-gen-2019 | Truglio, G | - |