Sfoglia per Autore
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors
2016-01-01 Brindisi, Margherita; Brogi, Simone; Giovani, Simone; Gemma, Sandra; Lamponi, Stefania; DE LUCA, Filomena; Novellino, Ettore; Campiani, Giuseppe; Docquier, JEAN DENIS; Butini, Stefania
Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem
2016-01-01 Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, Laurent; Nordmann, Patrice; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS
Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors
2016-01-01 Sgrignani, Jacopo; DE LUCA, Filomena; Torosyan, Hayarpi; Docquier, JEAN DENIS; Duan, Da; Novati, Beatrice; Prati, Fabio; Colombo, Giorgio; Grazioso, Giovanni
Mimicking the Ala220 Duplication of OXA-146 (an OXA-23 variant) in OXA-40 and OXA-48 Highlights Mechanistic Differences among Class D Carbapenemases.
2015-01-01 DE LUCA, Filomena; Pagliantini, Giorgio; Rossolini, GIAN MARIA; Docquier, JEAN DENIS
Occurrence of conjugative IncF-type plasmids harboring the bla CTX-M-15 gene in Enterobacteriaceae isolates from newborns in Tunisia
2015-01-01 Lahlaoui, Hella; DE LUCA, Filomena; Maradei, Simona; Ben Haj Khalifa, Anis; Ben Hamouda, Hechmi; Kheder, Mohamed; Ben Moussa, Mohamed; Rossollini, Gian Maria; Docquier, JEAN DENIS
Linear guanidine derivatives, methods of preparation and uses thereof
2015-01-01 Botta, Maurizio; Maccari, Giorgio; Sanfilippo, Stefania; DE LUCA, Filomena; Docquier, JEAN DENIS; Deodato, Davide
Interaction of Ceftaroline with Clinically-Relevant β-Lactamases
2015-01-01 DE LUCA, Filomena; Rossolini, GIAN MARIA; Docquier, JEAN DENIS
Characterization of a Functional Metallo-β-Lactamase from the Marine Bacterium Haliangium ochraceum
2015-01-01 Bianciardi, Simone; Borgianni, Luisa; DE LUCA, Filomena; Rossolini, GIAN MARIA; Docquier, JEAN DENIS
Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48.
2015-01-01 Lahiri, Sd; Mangani, Stefano; Jahić, H; Benvenuti, M; Durand Reville, Tf; DE LUCA, Filomena; Ehmann, De; Rossolini, GIAN MARIA; Alm, Ra; Docquier, JEAN DENIS
Biochemical Characterization of VIM-39, a VIM-1-Like Metallo-β-Lactamase Variant from a Multidrug-Resistant Klebsiella pneumoniae Isolate from Greece
2015-01-01 Papagiannitsis, Costas C; Pollini, Simona; DE LUCA, Filomena; Rossolini, GIAN MARIA; Docquier, JEAN DENIS; Hrabák, Jaroslav
Biochemical characterization of the POM-1 metallo-β-lactamase from Pseudomonas otitidis
2015-01-01 Borgianni, Luisa; DE LUCA, Filomena; Thaller, Maria Cristina; Chong, Yunsop; Rossolini, GIAN MARIA; Docquier, JEAN DENIS
New macrocyclic amidinourea derivatives, methods of preparation and uses thereof as chitinase inhibitors
2014-01-01 Sanfilippo, Stefania; Posteraro, Brunella; Sanguinetti, Maurizio; Botta, Maurizio; Maccari, Giorgio; DE LUCA, Filomena; Docquier, JEAN DENIS; Deodato, Davide
Evolution to carbapenem-hydrolyzing activity in class D β-lactamases by rational protein design.
2014-01-01 Pozzi, Cecilia; DI PISA, Flavio; DE LUCA, Filomena; Benvenuti, Manuela; Rossolini, GIAN MARIA; Docquier, JEAN DENIS; Mangani, Stefano
Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity
2014-01-01 Maccari, G.; Sanfilippo, S.; De Luca, F.; Deodato, D.; Casian, A.; Dasso Lang, M. C.; Zamperini, C.; Dreassi, E.; Rossolini, G. M.; Docquier, J. D.; Botta, M.
Microbiological analysis of hospital wastewaters: impact of water treatment on microbial biodiversity and antimicrobial resistance.
2013-01-01 TAPPA BROCCI, Niccolo'; DE LUCA, Filomena; Lenzi, D.; Basagni, C.; Rossolini, GIAN MARIA; Docquier, JEAN DENIS
Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam.
2013-01-01 Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, L.; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS
Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-Lactamases
2013-01-01 Lahiri, Sushmita D.; Mangani, Stefano; Durand-Reville, Thomas; Benvenuti, Manuela; De Luca, Filomena; Sanyal, Gautam; Docquier, Jean-Denis
Probing the role of R2-loop deletions and substituions on the functional properties of the acquired AmpC-type β-lactamase CMY-2.
2011-01-01 Cejas, D.; DE LUCA, Filomena; Gutkind, G.; Rossolini, GIAN MARIA; Radice, M.; Docquier, JEAN DENIS
Evolution to carbapenem -hydrolyzing activity in noncarbapenemase class D beta-lactamase OXA-10 by rational protein design
2011-01-01 DE LUCA, Filomena; Benvenuti, Manuela; Carboni, F; Pozzi, Cecilia; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS
Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates
2010-01-01 Docquier, JEAN DENIS; Benvenuti, Manuela; Calderone, V; Giuliani, F; Kapetis, D; DE LUCA, Filomena; Rossolini, GIAN MARIA; Mangani, Stefano
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors | 1-gen-2016 | Brindisi, Margherita; Brogi, Simone; Giovani, Simone; Gemma, Sandra; Lamponi, Stefania; DE LUCA, Filomena; Novellino, Ettore; Campiani, Giuseppe; Docquier, JEAN DENIS; Butini, Stefania | - | |
| Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem | 1-gen-2016 | Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, Laurent; Nordmann, Patrice; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS | - | |
| Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors | 1-gen-2016 | Sgrignani, Jacopo; DE LUCA, Filomena; Torosyan, Hayarpi; Docquier, JEAN DENIS; Duan, Da; Novati, Beatrice; Prati, Fabio; Colombo, Giorgio; Grazioso, Giovanni | - | |
| Mimicking the Ala220 Duplication of OXA-146 (an OXA-23 variant) in OXA-40 and OXA-48 Highlights Mechanistic Differences among Class D Carbapenemases. | 1-gen-2015 | DE LUCA, Filomena; Pagliantini, Giorgio; Rossolini, GIAN MARIA; Docquier, JEAN DENIS | - | |
| Occurrence of conjugative IncF-type plasmids harboring the bla CTX-M-15 gene in Enterobacteriaceae isolates from newborns in Tunisia | 1-gen-2015 | Lahlaoui, Hella; DE LUCA, Filomena; Maradei, Simona; Ben Haj Khalifa, Anis; Ben Hamouda, Hechmi; Kheder, Mohamed; Ben Moussa, Mohamed; Rossollini, Gian Maria; Docquier, JEAN DENIS | - | |
| Linear guanidine derivatives, methods of preparation and uses thereof | 1-gen-2015 | Botta, Maurizio; Maccari, Giorgio; Sanfilippo, Stefania; DE LUCA, Filomena; Docquier, JEAN DENIS; Deodato, Davide | - | |
| Interaction of Ceftaroline with Clinically-Relevant β-Lactamases | 1-gen-2015 | DE LUCA, Filomena; Rossolini, GIAN MARIA; Docquier, JEAN DENIS | - | |
| Characterization of a Functional Metallo-β-Lactamase from the Marine Bacterium Haliangium ochraceum | 1-gen-2015 | Bianciardi, Simone; Borgianni, Luisa; DE LUCA, Filomena; Rossolini, GIAN MARIA; Docquier, JEAN DENIS | - | |
| Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48. | 1-gen-2015 | Lahiri, Sd; Mangani, Stefano; Jahić, H; Benvenuti, M; Durand Reville, Tf; DE LUCA, Filomena; Ehmann, De; Rossolini, GIAN MARIA; Alm, Ra; Docquier, JEAN DENIS | - | |
| Biochemical Characterization of VIM-39, a VIM-1-Like Metallo-β-Lactamase Variant from a Multidrug-Resistant Klebsiella pneumoniae Isolate from Greece | 1-gen-2015 | Papagiannitsis, Costas C; Pollini, Simona; DE LUCA, Filomena; Rossolini, GIAN MARIA; Docquier, JEAN DENIS; Hrabák, Jaroslav | - | |
| Biochemical characterization of the POM-1 metallo-β-lactamase from Pseudomonas otitidis | 1-gen-2015 | Borgianni, Luisa; DE LUCA, Filomena; Thaller, Maria Cristina; Chong, Yunsop; Rossolini, GIAN MARIA; Docquier, JEAN DENIS | - | |
| New macrocyclic amidinourea derivatives, methods of preparation and uses thereof as chitinase inhibitors | 1-gen-2014 | Sanfilippo, Stefania; Posteraro, Brunella; Sanguinetti, Maurizio; Botta, Maurizio; Maccari, Giorgio; DE LUCA, Filomena; Docquier, JEAN DENIS; Deodato, Davide | - | |
| Evolution to carbapenem-hydrolyzing activity in class D β-lactamases by rational protein design. | 1-gen-2014 | Pozzi, Cecilia; DI PISA, Flavio; DE LUCA, Filomena; Benvenuti, Manuela; Rossolini, GIAN MARIA; Docquier, JEAN DENIS; Mangani, Stefano | - | |
| Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity | 1-gen-2014 | Maccari, G.; Sanfilippo, S.; De Luca, F.; Deodato, D.; Casian, A.; Dasso Lang, M. C.; Zamperini, C.; Dreassi, E.; Rossolini, G. M.; Docquier, J. D.; Botta, M. | - | |
| Microbiological analysis of hospital wastewaters: impact of water treatment on microbial biodiversity and antimicrobial resistance. | 1-gen-2013 | TAPPA BROCCI, Niccolo'; DE LUCA, Filomena; Lenzi, D.; Basagni, C.; Rossolini, GIAN MARIA; Docquier, JEAN DENIS | - | |
| Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam. | 1-gen-2013 | Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, L.; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS | - | |
| Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-Lactamases | 1-gen-2013 | Lahiri, Sushmita D.; Mangani, Stefano; Durand-Reville, Thomas; Benvenuti, Manuela; De Luca, Filomena; Sanyal, Gautam; Docquier, Jean-Denis | - | |
| Probing the role of R2-loop deletions and substituions on the functional properties of the acquired AmpC-type β-lactamase CMY-2. | 1-gen-2011 | Cejas, D.; DE LUCA, Filomena; Gutkind, G.; Rossolini, GIAN MARIA; Radice, M.; Docquier, JEAN DENIS | - | |
| Evolution to carbapenem -hydrolyzing activity in noncarbapenemase class D beta-lactamase OXA-10 by rational protein design | 1-gen-2011 | DE LUCA, Filomena; Benvenuti, Manuela; Carboni, F; Pozzi, Cecilia; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS | - | |
| Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates | 1-gen-2010 | Docquier, JEAN DENIS; Benvenuti, Manuela; Calderone, V; Giuliani, F; Kapetis, D; DE LUCA, Filomena; Rossolini, GIAN MARIA; Mangani, Stefano | - |
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