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Mostrati risultati da 1 a 20 di 124
Titolo Data di pubblicazione Autore(i) File Abstract
Alkaptonuria 1-gen-2024 Bernardini, Giulia; Braconi, Daniela; Zatkova, Andrea; Sireau, Nick; Kujawa, Mariusz J.; Introne, Wendy J.; Spiga, Ottavia; Geminiani, Michela; Gallagher, James A.; Ranganath, Lakshminarayan R.; Santucci, Annalisa -
3,3′-O-dimethylquercetin: a bi-functional vasodilator isolated from green propolis of the Caatinga Mimosa tenuiflora 1-gen-2024 Son, Ninh The; Gianibbi, Beatrice; Panti, Alice; Spiga, Ottavia; Bastos, Jairo Kenupp; Fusi, Fabio -
Electrophysiology, molecular modelling, and functional analysis of the effects of dietary quercetin and flavonoid analogues on Kir6.1 channels in rat stomach fundus smooth muscle 1-gen-2023 Pettini, Francesco; Spiga, Ottavia; Furini, Simone; Fusi, Fabio -
Structure-function relationship of homogentisate 1,2-dioxygenase: understanding the genotype-phenotype correlations in the rare genetic disease Alkaptonuria 1-gen-2023 Bernini, Andrea; Spiga, Ottavia; Santucci, Annalisa -
Dynamin-independent CaV1.2 and KCa1.1 channels regulation and vascular tone modulation by the mitochondrial fission inhibitors dynasore and dyngo-4a 1-gen-2023 Ahmed, Amer; Trezza, Alfonso; Gentile, Mariangela; Paccagnini, Eugenio; Panti, Alice; Lupetti, Pietro; Spiga, Ottavia; Bova, Sergio; Fusi, Fabio -
Omicron variants of SARS CoV-2 indicate a new antiviral strategy: Interfere with spike glycoprotein trimerization 1-gen-2023 Niccolai, Neri; Trezza, Alfonso; Marchini, Federico; Bongini, Pietro; Bianchini, Monica; Santucci, Annalisa; Spiga, Ottavia; Visibelli, Anna -
Vietnamese Dalbergia tonkinensis: A Promising Source of Mono- and Bifunctional Vasodilators 1-gen-2022 Cuong, Nguyen Manh; Son, Ninh The; Nhan, Ngu Truong; Fukuyama, Yoshiyasu; Ahmed, Amer; Saponara, Simona; Trezza, Alfonso; Gianibbi, Beatrice; Vigni, Ginevra; Spiga, Ottavia; Fusi, Fabio -
Effects of Nitisinone on Oxidative and Inflammatory Markers in Alkaptonuria: Results from SONIA1 and SONIA2 Studies 1-gen-2022 Braconi, Daniela; Geminiani, Michela; Psarelli, Eftychia Eirini; Giustarini, Daniela; Marzocchi, Barbara; Rossi, Ranieri; Bernardini, Giulia; Spiga, Ottavia; Gallagher, James A.; Le Quan Sang, Kim-Hanh; Arnoux, Jean-Baptiste; Imrich, Richard; Al-Sbou, Mohammed S.; Gornall, Matthew; Jackson, Richard; Ranganath, Lakshminarayan R.; Santucci, Annalisa -
Bioinformatics approaches to predict mutation effects in the binding site of the proangiogenic molecule {CD}93 1-gen-2022 Cicaloni, Vittoria; Karmakar, Malancha; Frusciante, Luisa; Pettini, Francesco; Visibelli, Anna; Orlandini, Maurizio; Galvagni, Federico; Mongiat, Maurizio; Silk, Michael; Nardi, Federica; Ascher, David; Santucci, Annalisa; Spiga, Ottavia -
Artificial intelligence approaches in drug discovery: towards the laboratory of the future 1-gen-2022 Frusciante, Luisa; Visibelli, Anna; Geminiani, Michela; Santucci, Annalisa; Spiga, Ottavia -
Structural bioinformatic survey of protein-small molecule interfaces delineates the role of glycine in surface pocket formation 1-gen-2022 Bongini, Pietro; Niccolai, Neri; Trezza, Alfonso; Mangiavacchi, Guido; Santucci, Annalisa; Spiga, Ottavia; Bianchini, Monica; Gardini, Simone -
The pharmacogenetics of cannabis in the treatment of chronic pain 1-gen-2022 Poli, Paolo; Peruzzi, Luana; Maurizi, Pierdomenico; Mencucci, Antonella; Scocca, Antonella; Carnevale, Simona; Spiga, Ottavia; Santucci, Annalisa -
HGDiscovery: an online tool providing functional and phenotypic information on novel variants of homogentisate 1,2- dioxigenase 1-gen-2022 Karmakar, Malancha; Cicaloni, Vittoria; Rodrigues, Carlos H M; Spiga, Ottavia; Santucci, Annalisa; Ascher, David B -
Homogentisic acid induces autophagy alterations leading to chondroptosis in human chondrocytes: Implications in Alkaptonuria 1-gen-2022 Galderisi, S.; Milella, M. S.; Rossi, M.; Cicaloni, V.; Rossi, R.; Giustarini, D.; Spiga, O.; Tinti, L.; Salvini, L.; Tinti, C.; Braconi, D.; Millucci, L.; Lupetti, P.; Prischi, F.; Bernardini, G.; Santucci, A. -
The drp-1-mediated mitochondrial fission inhibitor mdivi-1 impacts the function of ion channels and pathways underpinning vascular smooth muscle tone 1-gen-2022 Ahmed, Amer; Trezza, Alfonso; Gentile, Mariangela; Paccagnini, Eugenio; Lupetti, Pietro; Spiga, Ottavia; Bova, Sergio; Fusi, Fabio -
In silico multi-target approach revealed potential lead compounds as scaffold for the synthesis of chemical analogues targeting SARS-CoV-2 1-gen-2022 Trezza, Alfonso; Mugnaini, Claudia; Corelli, Federico; Santucci, Annalisa; Spiga, Ottavia -
Pharmacological and in silico analysis of oat avenanthramides as EGFR inhibitors: effects on EGF-induced lung cancer cell growth and migration 1-gen-2022 Trabalzini, Lorenza; Ercoli, Jasmine; Trezza, Alfonso; Schiavo, Irene; Macrì, Giulia; Moglia, Andrea; Spiga, Ottavia; Finetti, Federica -
Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts 1-gen-2022 Bisi, Alessandra; Feoli, Alessandra; Trezza, Alfonso; Viejo, Lucia; Formaggio, Francesco; Bartolini, Manuela; Belluti, Federica; Gobbi, Silvia; Spiga, Ottavia; Caprini, Marco; de Los Rios, Cristobal; Castellano, Sabrina; Rampa, Angela -
Functional, electrophysiology, and molecular dynamics analysis of quercetin-induced contraction of rat vascular musculature 1-gen-2022 Trezza, A.; Spiga, O.; Mugnai, P.; Saponara, S.; Sgaragli, G.; Fusi, F. -
Computational approaches integrated in a digital ecosystem platform for a rare disease 1-gen-2022 Visibelli, Anna; Cicaloni, Vittoria; Spiga, Ottavia; Santucci, Annalisa -
Mostrati risultati da 1 a 20 di 124
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