We describe an unusual case of a recurrent dural neoplasm, previously diagnosed as meningioma. Histopathologically, the tumor is characterized by aggregates of divergently differentiated clear cells embedded in an abundant lymphoplasmacyte-rich stroma, mimicking a lymphoplasmacyte-rich meningioma. This study focuses on the histologic and immunohistochemical characterization of a unique dural-based tumor and provides useful guidelines for differentiating meningioma from other uncommon dural-based neoplasms. We propose that this recurrent dural neoplasm is a distinctive entity and, therefore, enlarges the spectrum of dural-based neoplasms that enter the differential diagnosis with meningiomas. Awareness of this tumor entity could prove useful for appropriate patient management.

Miracco, C., Toscano, M., Butorano, M.A.G.M., Baldino, G., Tacchini, D., Barone, A., et al. (2015). Unusual clear cell, lymphoplasmacyte-rich, dural-based tumor with divergent differentiation: A tricky case mimicking a meningioma. HUMAN PATHOLOGY, 46(7), 1050-1056 [10.1016/j.humpath.2015.03.006].

Unusual clear cell, lymphoplasmacyte-rich, dural-based tumor with divergent differentiation: A tricky case mimicking a meningioma

MIRACCO, CLELIA;TOSCANO, MARZIA;BUTORANO, MARIE AIMEE GLORIA MUNEZERO;TACCHINI, DAMIANA;BARONE, AURORA;CERASE, ALFONSO
2015-01-01

Abstract

We describe an unusual case of a recurrent dural neoplasm, previously diagnosed as meningioma. Histopathologically, the tumor is characterized by aggregates of divergently differentiated clear cells embedded in an abundant lymphoplasmacyte-rich stroma, mimicking a lymphoplasmacyte-rich meningioma. This study focuses on the histologic and immunohistochemical characterization of a unique dural-based tumor and provides useful guidelines for differentiating meningioma from other uncommon dural-based neoplasms. We propose that this recurrent dural neoplasm is a distinctive entity and, therefore, enlarges the spectrum of dural-based neoplasms that enter the differential diagnosis with meningiomas. Awareness of this tumor entity could prove useful for appropriate patient management.
2015
Miracco, C., Toscano, M., Butorano, M.A.G.M., Baldino, G., Tacchini, D., Barone, A., et al. (2015). Unusual clear cell, lymphoplasmacyte-rich, dural-based tumor with divergent differentiation: A tricky case mimicking a meningioma. HUMAN PATHOLOGY, 46(7), 1050-1056 [10.1016/j.humpath.2015.03.006].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/982411
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