A general, mild and efficient procedure with which to access hydroxamic acids, in good yields and purity, is reported. Esters are used as substrates and reacted with hydroxylamine, in the presence of a base, under microwave activation. The method has been successfully applied to enantiomerically pure esters without loss of stereochemical integrity.

Massaro, A., Mordini, A., Reginato, G., Russo, F., Taddei, M. (2007). Microwave-assisted transformation of esters into hydroxamic acids. SYNTHESIS(20), 3201-3204 [10.1055/s-2007-990803].

Microwave-assisted transformation of esters into hydroxamic acids

Taddei, Maurizio
2007-01-01

Abstract

A general, mild and efficient procedure with which to access hydroxamic acids, in good yields and purity, is reported. Esters are used as substrates and reacted with hydroxylamine, in the presence of a base, under microwave activation. The method has been successfully applied to enantiomerically pure esters without loss of stereochemical integrity.
2007
Massaro, A., Mordini, A., Reginato, G., Russo, F., Taddei, M. (2007). Microwave-assisted transformation of esters into hydroxamic acids. SYNTHESIS(20), 3201-3204 [10.1055/s-2007-990803].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/9243
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