A general, mild and efficient procedure with which to access hydroxamic acids, in good yields and purity, is reported. Esters are used as substrates and reacted with hydroxylamine, in the presence of a base, under microwave activation. The method has been successfully applied to enantiomerically pure esters without loss of stereochemical integrity.
Massaro, A., Mordini, A., Reginato, G., Russo, F., Taddei, M. (2007). Microwave-assisted transformation of esters into hydroxamic acids. SYNTHESIS(20), 3201-3204 [10.1055/s-2007-990803].
Microwave-assisted transformation of esters into hydroxamic acids
Taddei, Maurizio
2007-01-01
Abstract
A general, mild and efficient procedure with which to access hydroxamic acids, in good yields and purity, is reported. Esters are used as substrates and reacted with hydroxylamine, in the presence of a base, under microwave activation. The method has been successfully applied to enantiomerically pure esters without loss of stereochemical integrity.File in questo prodotto:
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https://hdl.handle.net/11365/9243
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