A rapid protocol for the multicomponent microwave-assisted organocatalytic domino Knoevenagel/hetero Diels–Alder reaction (DKHDA) has been developed for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. The reported procedure could be used for the fast generation of novel substituted 2,3-dihydropyran[2,3-c]pyrazoles with potential anti-tuberculosis activity.
Radi, M., Bernardo, V., Bechi, B., Castagnolo, D., Pagano, M., Botta, M. (2009). Microwave-assisted organocatalytic multicomponent Knoevenagel/Hetero Diels Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. TETRAHEDRON LETTERS, 50, 6572-6575 [10.1016/j.tetlet.2009.09.047].
Microwave-assisted organocatalytic multicomponent Knoevenagel/Hetero Diels Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles
RADI, MARCO;BERNARDO, VINCENZO;BECHI, BEATRICE;CASTAGNOLO, DANIELE;PAGANO, MAFALDA;BOTTA, MAURIZIO
2009-01-01
Abstract
A rapid protocol for the multicomponent microwave-assisted organocatalytic domino Knoevenagel/hetero Diels–Alder reaction (DKHDA) has been developed for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. The reported procedure could be used for the fast generation of novel substituted 2,3-dihydropyran[2,3-c]pyrazoles with potential anti-tuberculosis activity.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/9219
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo