Despite the fact that many of the physiological roles of taurine are still obscure, a series of experimental data have been published suggesting that taurine can have a function in the modulation of calcium fluxes at cardiac level [1-3] and at the level of liver mitochondria [4]. It was suggested that the interference of taurine with calcium fluxes could be interpreted as the result of the formation of a calcium-taurine complex [1-4]. This hypothesis was rejected in a paper of Igisu et al. [5]. We have further investigated this point by means of Fourier Transform 13C nuclear magnetic resonance (13C-FT-NMR). In recent years it was in fact demonstrated that this is a powerful tool for the study of weak ligand-metal interactions. [6]. © 1978.

Dolara, P., Franconi, F., Giotti, A., Basosi, R., Valensin, G. (1978). Taurine-calcium interaction measured by means of 13C-NMR. BIOCHEMICAL PHARMACOLOGY, 27(5), 803-804 [10.1016/0006-2952(78)90526-9].

Taurine-calcium interaction measured by means of 13C-NMR

Basosi, Riccardo;Valensin, Gianni
1978-01-01

Abstract

Despite the fact that many of the physiological roles of taurine are still obscure, a series of experimental data have been published suggesting that taurine can have a function in the modulation of calcium fluxes at cardiac level [1-3] and at the level of liver mitochondria [4]. It was suggested that the interference of taurine with calcium fluxes could be interpreted as the result of the formation of a calcium-taurine complex [1-4]. This hypothesis was rejected in a paper of Igisu et al. [5]. We have further investigated this point by means of Fourier Transform 13C nuclear magnetic resonance (13C-FT-NMR). In recent years it was in fact demonstrated that this is a powerful tool for the study of weak ligand-metal interactions. [6]. © 1978.
1978
Dolara, P., Franconi, F., Giotti, A., Basosi, R., Valensin, G. (1978). Taurine-calcium interaction measured by means of 13C-NMR. BIOCHEMICAL PHARMACOLOGY, 27(5), 803-804 [10.1016/0006-2952(78)90526-9].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/7118
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