Arrhenius parameters were measured for the methoxy‐lechlorination reactions of some chloroderivatives of isoxazolo[4,5‐c]‐ and [5,4‐b]pyridine. A comparison of these results with the kinetic data for the corresponding chloropyridines shows that fusion of the isoxazole ring with the pyridine ring strongly increases the reactivity of the 4‐ and 6‐positions toward nucleophilic substitution. Copyright © 1979 Journal of Heterocyclic Chemistry
Adembri, G., Ponticelli, F., Camparini, A., Tedeschi, P. (1979). The Kinetic of the Reaction of some Chloroisoxazolo[4,5-c] and [5,4-b]pyridines with the Methoxide Ion. JOURNAL OF HETEROCYCLIC CHEMISTRY, 16(1), 49-51 [10.1002/jhet.5570160111].
The Kinetic of the Reaction of some Chloroisoxazolo[4,5-c] and [5,4-b]pyridines with the Methoxide Ion
Adembri, Giorgio;Ponticelli, Fabio;Camparini, Alfredo;
1979-01-01
Abstract
Arrhenius parameters were measured for the methoxy‐lechlorination reactions of some chloroderivatives of isoxazolo[4,5‐c]‐ and [5,4‐b]pyridine. A comparison of these results with the kinetic data for the corresponding chloropyridines shows that fusion of the isoxazole ring with the pyridine ring strongly increases the reactivity of the 4‐ and 6‐positions toward nucleophilic substitution. Copyright © 1979 Journal of Heterocyclic Chemistry
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https://hdl.handle.net/11365/6707
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