The invention provides methods for the detection of mutations and polymorphisms in the pRb2/p130 gene, which may be used to characterize genetic events associated with tumor formation, to trace the parental origin of mutatations, to identify carriers of germline mutations, and to identify individuals with a predisposition to cancer.
Giordano, A., A., B. (1998)“Human Retinoblastoma-Related (pRb2/p130) Genomic DNA and Methods of Detecting Mutations Therein.". . Brevetto No. US5807681a.
“Human Retinoblastoma-Related (pRb2/p130) Genomic DNA and Methods of Detecting Mutations Therein."
GIORDANO, ANTONIO;
1998-01-01
Abstract
The invention provides methods for the detection of mutations and polymorphisms in the pRb2/p130 gene, which may be used to characterize genetic events associated with tumor formation, to trace the parental origin of mutatations, to identify carriers of germline mutations, and to identify individuals with a predisposition to cancer.
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https://hdl.handle.net/11365/4942
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