Osteogenic proteins (OP) are elements of a class of natural growth factors called Bone Morphogenetic Proteins (BMP). A specific member of this class is OP-1, a human recombinant protein that has osteogenic properties. The osteoinductive and osteoconductive properties of OP-1, with its specific collagen matrix, promote the generation of new functionally active, biologically and biomechanically mature bone. We carried out a clinical study to verify the potential of this protein in fresh tibial closed fractures, using OP-1 associated with osteosynthesis by means of a monolateral external fixator.

Maniscalco, P., Gambera, D., Bertone, C., Rivera, F., Crainz, E., Urgelli, S. (2002). Healing of fresh tibial fractures with OP-1. A preliminary report. ACTA BIO-MEDICA DE L'ATENEO PARMENSE, 73(1-2), 7-10.

Healing of fresh tibial fractures with OP-1. A preliminary report

Maniscalco P.;
2002-01-01

Abstract

Osteogenic proteins (OP) are elements of a class of natural growth factors called Bone Morphogenetic Proteins (BMP). A specific member of this class is OP-1, a human recombinant protein that has osteogenic properties. The osteoinductive and osteoconductive properties of OP-1, with its specific collagen matrix, promote the generation of new functionally active, biologically and biomechanically mature bone. We carried out a clinical study to verify the potential of this protein in fresh tibial closed fractures, using OP-1 associated with osteosynthesis by means of a monolateral external fixator.
2002
Maniscalco, P., Gambera, D., Bertone, C., Rivera, F., Crainz, E., Urgelli, S. (2002). Healing of fresh tibial fractures with OP-1. A preliminary report. ACTA BIO-MEDICA DE L'ATENEO PARMENSE, 73(1-2), 7-10.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/41028
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