A series of 2-arylpyrazolo[4,3-c] quinolin-3-one derivatives, bearing different substituents in the two aromatic rings, were prepared and tested for their ability to displace [H-3] flunitrazepam from rat brain membranes. Some compounds have shown an affinity for receptors comparable and sometimes higher than that of CGS series.
Savini, L., Massarelli, P., Pellerano, C., Fiorini, I., Bruni, G., Romeo, M.R. (1993). Pyrazolo[4,3-c]quinolines. Synthesis and specific inhibition of benzodiazepine receptor binding (Note I). IL FARMACO, 48(1), 65-76.
Pyrazolo[4,3-c]quinolines. Synthesis and specific inhibition of benzodiazepine receptor binding (Note I)
SAVINI, LUISA;MASSARELLI, PAOLA;PELLERANO, CESARE;FIORINI, ISABELLA;BRUNI, GIANCARLO;
1993-01-01
Abstract
A series of 2-arylpyrazolo[4,3-c] quinolin-3-one derivatives, bearing different substituents in the two aromatic rings, were prepared and tested for their ability to displace [H-3] flunitrazepam from rat brain membranes. Some compounds have shown an affinity for receptors comparable and sometimes higher than that of CGS series.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Il Farmaco 1993, 48(1),65-76.pdf
non disponibili
Descrizione: Articolo principale
Tipologia:
PDF editoriale
Licenza:
NON PUBBLICO - Accesso privato/ristretto
Dimensione
4.73 MB
Formato
Adobe PDF
|
4.73 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/402195
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo