Calcitonin gene-related peptide (CGRP) circulates in maternal circulation throughout pregnancy, and specific receptors for CGRP (CGRPrs) are expressed by human myometrium. Because CGRP induces a dose-dependent relaxation of human myometrium, we examined a role for CGRP in modulation of myometrial smooth muscle contractility during pregnancy and labor. The aim of the present study was to evaluate the changes of maternal serum CGRP levels during parturition, according to the mode of delivery and in relation to cervical dilatation.
Florio, P., Margutti, A., Apa, R., Miceli, ..F., Pezzani, I., DEGLI UBERTI, E.C., et al. (2001). Maternal plasma calcitonin gene-related peptide levels do not change during labor and are not influenced by delivery route. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, 8(3), 165-168 [10.1016/S1071-5576(01)00103-4].
Maternal plasma calcitonin gene-related peptide levels do not change during labor and are not influenced by delivery route
FLORIO, P.;
2001-01-01
Abstract
Calcitonin gene-related peptide (CGRP) circulates in maternal circulation throughout pregnancy, and specific receptors for CGRP (CGRPrs) are expressed by human myometrium. Because CGRP induces a dose-dependent relaxation of human myometrium, we examined a role for CGRP in modulation of myometrial smooth muscle contractility during pregnancy and labor. The aim of the present study was to evaluate the changes of maternal serum CGRP levels during parturition, according to the mode of delivery and in relation to cervical dilatation.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/19839
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo