We have previously reported the development of CB-25 and CB-52, two ligands of CB1 and CB2 cannabinoid receptors. We assessed here their functional activity. The effect of the two compounds on forskolin-induced cAMP formation in intact cells or GTP-g-S binding to cell membranes, and their action on nociception in vivo was determined.

M. G., C., T., B., E., P., A., T., M., V.D.S., Brizzi, A., et al. (2006). In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands. BRITISH JOURNAL OF PHARMACOLOGY, 149, 431-440 [10.1038/sj.bjp.0706888].

In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands

BRIZZI, ANTONELLA;BRIZZI, VITTORIO;
2006-01-01

Abstract

We have previously reported the development of CB-25 and CB-52, two ligands of CB1 and CB2 cannabinoid receptors. We assessed here their functional activity. The effect of the two compounds on forskolin-induced cAMP formation in intact cells or GTP-g-S binding to cell membranes, and their action on nociception in vivo was determined.
2006
M. G., C., T., B., E., P., A., T., M., V.D.S., Brizzi, A., et al. (2006). In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands. BRITISH JOURNAL OF PHARMACOLOGY, 149, 431-440 [10.1038/sj.bjp.0706888].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/18520
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