An amidic derivative of a carboxymethylcellulose-based hydrogel was obtained and characterized in terms of amidation degree. NMR studies and FT-IR imaging spectroscopy demonstrated that the reaction allowed a polymer to be obtained that was characterized by a regular distribution of amidic groups along the polysaccharide chains. Through this regularity, a homogenous three-dimensional scaffold was obtained, which maintained the thixotropic property of the linear polysaccharide.
Leone, G., Maurizio, D., MARIA ENRICA DI, C., Anna, B., Barbucci, R. (2008). The applicability of an amidated polysaccharide hydrogel as a cartilage substitute: Structural and Rheological Characterisation. CARBOHYDRATE RESEARCH, 343, 317-327 [10.1016/j.carres.2007.10.017].
The applicability of an amidated polysaccharide hydrogel as a cartilage substitute: Structural and Rheological Characterisation
LEONE, GEMMA;BARBUCCI, ROLANDO
2008-01-01
Abstract
An amidic derivative of a carboxymethylcellulose-based hydrogel was obtained and characterized in terms of amidation degree. NMR studies and FT-IR imaging spectroscopy demonstrated that the reaction allowed a polymer to be obtained that was characterized by a regular distribution of amidic groups along the polysaccharide chains. Through this regularity, a homogenous three-dimensional scaffold was obtained, which maintained the thixotropic property of the linear polysaccharide.
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https://hdl.handle.net/11365/12371
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