The expression pattern of c-sis, c-fos and c-jun was investigated in placenta and embryofetal organ specimens from the first trimester. Northern analysis of the placentae showed c-sis transcripts and c-fos expression. Northern analysis of the same genes in embryofetal organs pointed to the brain as the only organ where consistent transcriptional activity could be observed. RT-PCR analysis of c-fos and c-jun in placentae, staged at four different time periods in pregnancy, allowed to detect the expected fragments in all cases. The same was true when c-fos and c-jun were analyzed at the 13th week of gestation in all the embryofetal organs.
Rossi, D., DEL GIACCO, L., Doneda, L., Acaia, B., Brioschi, D., Nicolini, U., et al. (1996). Expression pattern of c-sis, c-fos and c-jun in human placenta and embryofoetal organs. GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 42(1), 1-7 [10.1159/000291878].
Expression pattern of c-sis, c-fos and c-jun in human placenta and embryofoetal organs
ROSSI, D.;
1996-01-01
Abstract
The expression pattern of c-sis, c-fos and c-jun was investigated in placenta and embryofetal organ specimens from the first trimester. Northern analysis of the placentae showed c-sis transcripts and c-fos expression. Northern analysis of the same genes in embryofetal organs pointed to the brain as the only organ where consistent transcriptional activity could be observed. RT-PCR analysis of c-fos and c-jun in placentae, staged at four different time periods in pregnancy, allowed to detect the expected fragments in all cases. The same was true when c-fos and c-jun were analyzed at the 13th week of gestation in all the embryofetal organs.
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https://hdl.handle.net/11365/10389
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