The present invention concerns novel pyrrole compounds, derivatives of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine (BM212). The invention concerns the use of the described compounds as antitubercular agents and a process to obtain intermediates and final compounds. The compounds of the invention are found to be more active and much less toxic than previously known compounds.

Biava, M., Porretta, G.c., Pompei, R., Botta, M., Manetti, F., De Logu, A. (2013)Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto. . Brevetto No. EP2195289B1.

Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto

BOTTA, MAURIZIO;MANETTI, FABRIZIO;
2013-01-01

Abstract

The present invention concerns novel pyrrole compounds, derivatives of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine (BM212). The invention concerns the use of the described compounds as antitubercular agents and a process to obtain intermediates and final compounds. The compounds of the invention are found to be more active and much less toxic than previously known compounds.
2013
Biava, M., Porretta, G.c., Pompei, R., Botta, M., Manetti, F., De Logu, A. (2013)Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto. . Brevetto No. EP2195289B1.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/1011101
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