Sfoglia per Autore
Rational design of the first difluorostatone-based PfSUB1 inhibitors
2014-01-01 Giovani, Simone; Maria, Penzo; Brogi, Simone; Brindisi, Margherita; Gemma, Sandra; Ettore, Novellino; Savini, Luisa; Michael J., Blackman; Campiani, Giuseppe; Butini, Stefania
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1
2012-01-01 Gemma, Sandra; Giovani, Simone; Brindisi, Margherita; Tripaldi, Pierangela; Brogi, Simone; Savini, Luisa; Fiorini, Isabella; Ettore, Novellino; Butini, Stefania; Campiani, Giuseppe; Maria, Penzo; Michael J., Blackman
Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents
2012-01-01 Gemma, Sandra; Camodeca, Caterina; Brindisi, Margherita; Brogi, Simone; Gagan, Kukreja; Kunjir, SANIL ASHOK; Emanuele, Gabellieri; Leonardo, Lucantoni; Annette, Habluetzel; Donatella, Taramelli; Nicoletta, Basilico; Roberta, Gualdani; Francesco Tadini, Buoninsegni; Gianluca, Bartolommei; Maria Rosa, Moncelli; Rowena E., Martin; Robert L., Summers; Lamponi, Stefania; Savini, Luisa; Fiorini, Isabella; Valoti, Massimo; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania
Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling
2012-01-01 Gemma, Sandra; Camodeca, Caterina; SANNA COCCONE, Salvatore; Bhupendra P., Joshi; Bernetti, Matteo; Moretti, Vittoria; Brogi, Simone; María Cruz, Bonache; Savini, Luisa; Donatella, Taramelli; Nicoletta, Basilico; Silvia, Parapini; Matthias, Rottmann; Reto, Brun; Lamponi, Stefania; Silvio, Caccia; Giovanna, Guiso; Robert, Summer; Rowena, Martin; Saponara, Simona; Gorelli, Beatrice; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania
Pyrroloquinoxaline hydrazones as fluorescent probes for amyloid fibrils
2011-01-01 Gemma, Sandra; Laura, Colombo; Gianluigi, Forloni; Savini, Luisa; Claudia, Fracasso; Silvio, Caccia; Mario, Salmona; Brindisi, Margherita; BHUPENDRA P., Joshi; Tripaldi, Pierangela; Giorgi, Gianluca; ORAZIO TAGLIALATELA, Scafati; Ettore, Novellino; Fiorini, Isabella; Campiani, Giuseppe; Butini, Stefania
Malaria chemotherapy: recent advances in drug development
2010-01-01 Gemma, Sandra; Travagli, Valter; Savini, Luisa; Novellino, E; Campiani, Giuseppe; Butini, Stefania
Development of Antitubercular Compounds Based on a 4-Quinolylhydrazone Scaffold. Further Structure-activity Relationship Studies.
2009-01-01 Gemma, Sandra; Savini, Luisa; Altarelli, Maria; Tripaldi, Pierangela; Chiasserini, Luisa; SANNA COCCONE, Salvatore; Vinod, Kumar; Camodeca, Caterina; Campiani, Giuseppe; Ettore, Novellino; Sandra, Clarizio; Giovanni, Delogu; Butini, Stefania
Microwave-assisted synthesis of 4-quinolylhydrazines followed by nickel boride reduction: a convenient approach to 4-aminoquinolines and derivatives
2008-01-01 Gemma, Sandra; G., Kukreja; Tripaldi, Pierangela; Altarelli, Maria; Bernetti, Matteo; Franceschini, Silvia; Savini, Luisa; Campiani, Giuseppe; C., Fattorusso; Butini, Stefania
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents.
2008-01-01 C., Fattorusso; Campiani, Giuseppe; G., Kukreja; M., Persico; Butini, Stefania; Romano, MARIA PIA; Altarelli, Maria; S., Ros; Brindisi, Margherita; Savini, Luisa; E., Novellino; Nacci, Vito; E., Fattorusso; S., Parapini; N., Basilico; D., Taramelli; V., Yardley; S., Croft; M., Borriello; Gemma, Sandra
Clotrimazole Scaffold as an Innovative Pharmacophore Towards Potent Antimalarial Agents: Design, Synthesis, Biological and Structure-Activity Relationship Studies.
2008-01-01 Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; G., Kukreja; SANNA COCCONE, Salvatore; B., Joshi; M., Persico; Nacci, Vito; Fiorini, Isabella; E., Novellino; Fattorusso, E; O., TAGLIALATELA SCAFATI; Savini, Luisa; D., Taramelli; N., Basilico; S., Parapini; G., Morace; V., Yardley; S., Croft; M., Coletta; S., Marini; Fattorusso, Caterina
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.
2007-01-01 Gemma, Sandra; Kukreja, G; Campiani, Giuseppe; Butini, Stefania; Bernetti, Matteo; Joshi, Bp; Savini, Luisa; Basilico, N; Taramelli, D; Yardley, V; Bertamino, A; Novellino, E; Persico, M; Catalanotti, B; Fattorusso, C.
ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE
2007-01-01 Campiani, Giuseppe; Gemma, Sandra; C., Fattorusso; G., Kukreja; B. P., Joshi; O., TAGLIALATELA SCAFATI; Savini, Luisa; M., DE ANGELIS; E., Fattorusso
Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore.
2007-01-01 Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; B., Joshi; G., Kukreja; M., Persico; B., Catalanotti; E., Novellino; Fattorusso, E; Nacci, Vito; Savini, Luisa; D., Taramelli; N., Basilico; G., Morace; V., Yardley; C., Fattorusso
Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.
2006-01-01 Gemma, Sandra; G., Kukreja; C., Fattorusso; M., Persico; Romano, MARIA PIA; Altarelli, Maria; Savini, Luisa; Campiani, Giuseppe; Fattorusso, E; N., Basilico; D., Taramelli; V., Yardley; Butini, Stefania
Structural study of ribonucleotide reductase inhibitor hydrazones. Synthesis and X-ray diffraction analysis of a copper(II)-benzoylpyridine-2-quinolinyl hydrazone complex
2005-01-01 Tamasi, Gabriella; Chiasserini, Luisa; Savini, Luisa; Sega, Alessandro; Cini, Renzo
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors.
2005-01-01 Campiani, Giuseppe; Fattorusso, C; Butini, Stefania; Gaeta, A; Agnusdei, M; Gemma, Sandra; Persico, M; Catalanotti, B; Savini, Luisa; Nacci, Vito; Novellino, E; Holloway, Hw; Greig, Nh; Belinskaya, T; Fedorko, Jm; Saxena, A.
Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663
2005-01-01 G., Maga; Gemma, Sandra; C., Fattorusso; G. A., Locatelli; Butini, Stefania; M., Persico; G., Kukreja; Romano, MARIA PIA; Chiasserini, Luisa; Savini, Luisa; E., Novellino; Nacci, Vito; S., Spadari; Campiani, Giuseppe
New alpha-(N)-heterocyclichydrazones: evaluation of anticancer, anti-HIV and antimicrobial activity.
2004-01-01 Savini, Luisa; Chiasserini, Luisa; Travagli, Valter; Pellerano, Cesare; Novellino, E.; Cosentino, S.; Pisano, M. B.
Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors
2003-01-01 Savini, L.; Gaeta, A.; Fattorusso, C.; Catalanotti, B.; Campiani, G.; Chiasserini, L.; Pellerano, C.; Novellino, E.; Mckissic, D.; Saxena, A.
Novel and potent tacrine-related hetero- and homobivalent ligands for acetylcholinesterase and butyrylcholinesterase
2001-01-01 Savini, Luisa; Campiani, Giuseppe; Gaeta, Alessandra; Pellerano, Cesare; Fattorusso, Caterina; Chiasserini, Luisa; Fedorko, James M.; Saxena, Ashima
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Rational design of the first difluorostatone-based PfSUB1 inhibitors | 1-gen-2014 | Giovani, Simone; Maria, Penzo; Brogi, Simone; Brindisi, Margherita; Gemma, Sandra; Ettore, Novellino; Savini, Luisa; Michael J., Blackman; Campiani, Giuseppe; Butini, Stefania | - | |
| Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 | 1-gen-2012 | Gemma, Sandra; Giovani, Simone; Brindisi, Margherita; Tripaldi, Pierangela; Brogi, Simone; Savini, Luisa; Fiorini, Isabella; Ettore, Novellino; Butini, Stefania; Campiani, Giuseppe; Maria, Penzo; Michael J., Blackman | - | |
| Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents | 1-gen-2012 | Gemma, Sandra; Camodeca, Caterina; Brindisi, Margherita; Brogi, Simone; Gagan, Kukreja; Kunjir, SANIL ASHOK; Emanuele, Gabellieri; Leonardo, Lucantoni; Annette, Habluetzel; Donatella, Taramelli; Nicoletta, Basilico; Roberta, Gualdani; Francesco Tadini, Buoninsegni; Gianluca, Bartolommei; Maria Rosa, Moncelli; Rowena E., Martin; Robert L., Summers; Lamponi, Stefania; Savini, Luisa; Fiorini, Isabella; Valoti, Massimo; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania | - | |
| Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling | 1-gen-2012 | Gemma, Sandra; Camodeca, Caterina; SANNA COCCONE, Salvatore; Bhupendra P., Joshi; Bernetti, Matteo; Moretti, Vittoria; Brogi, Simone; María Cruz, Bonache; Savini, Luisa; Donatella, Taramelli; Nicoletta, Basilico; Silvia, Parapini; Matthias, Rottmann; Reto, Brun; Lamponi, Stefania; Silvio, Caccia; Giovanna, Guiso; Robert, Summer; Rowena, Martin; Saponara, Simona; Gorelli, Beatrice; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania | - | |
| Pyrroloquinoxaline hydrazones as fluorescent probes for amyloid fibrils | 1-gen-2011 | Gemma, Sandra; Laura, Colombo; Gianluigi, Forloni; Savini, Luisa; Claudia, Fracasso; Silvio, Caccia; Mario, Salmona; Brindisi, Margherita; BHUPENDRA P., Joshi; Tripaldi, Pierangela; Giorgi, Gianluca; ORAZIO TAGLIALATELA, Scafati; Ettore, Novellino; Fiorini, Isabella; Campiani, Giuseppe; Butini, Stefania | - | |
| Malaria chemotherapy: recent advances in drug development | 1-gen-2010 | Gemma, Sandra; Travagli, Valter; Savini, Luisa; Novellino, E; Campiani, Giuseppe; Butini, Stefania | - | |
| Development of Antitubercular Compounds Based on a 4-Quinolylhydrazone Scaffold. Further Structure-activity Relationship Studies. | 1-gen-2009 | Gemma, Sandra; Savini, Luisa; Altarelli, Maria; Tripaldi, Pierangela; Chiasserini, Luisa; SANNA COCCONE, Salvatore; Vinod, Kumar; Camodeca, Caterina; Campiani, Giuseppe; Ettore, Novellino; Sandra, Clarizio; Giovanni, Delogu; Butini, Stefania | - | |
| Microwave-assisted synthesis of 4-quinolylhydrazines followed by nickel boride reduction: a convenient approach to 4-aminoquinolines and derivatives | 1-gen-2008 | Gemma, Sandra; G., Kukreja; Tripaldi, Pierangela; Altarelli, Maria; Bernetti, Matteo; Franceschini, Silvia; Savini, Luisa; Campiani, Giuseppe; C., Fattorusso; Butini, Stefania | - | |
| Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents. | 1-gen-2008 | C., Fattorusso; Campiani, Giuseppe; G., Kukreja; M., Persico; Butini, Stefania; Romano, MARIA PIA; Altarelli, Maria; S., Ros; Brindisi, Margherita; Savini, Luisa; E., Novellino; Nacci, Vito; E., Fattorusso; S., Parapini; N., Basilico; D., Taramelli; V., Yardley; S., Croft; M., Borriello; Gemma, Sandra | - | |
| Clotrimazole Scaffold as an Innovative Pharmacophore Towards Potent Antimalarial Agents: Design, Synthesis, Biological and Structure-Activity Relationship Studies. | 1-gen-2008 | Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; G., Kukreja; SANNA COCCONE, Salvatore; B., Joshi; M., Persico; Nacci, Vito; Fiorini, Isabella; E., Novellino; Fattorusso, E; O., TAGLIALATELA SCAFATI; Savini, Luisa; D., Taramelli; N., Basilico; S., Parapini; G., Morace; V., Yardley; S., Croft; M., Coletta; S., Marini; Fattorusso, Caterina | - | |
| Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling. | 1-gen-2007 | Gemma, Sandra; Kukreja, G; Campiani, Giuseppe; Butini, Stefania; Bernetti, Matteo; Joshi, Bp; Savini, Luisa; Basilico, N; Taramelli, D; Yardley, V; Bertamino, A; Novellino, E; Persico, M; Catalanotti, B; Fattorusso, C. | - | |
| ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | 1-gen-2007 | Campiani, Giuseppe; Gemma, Sandra; C., Fattorusso; G., Kukreja; B. P., Joshi; O., TAGLIALATELA SCAFATI; Savini, Luisa; M., DE ANGELIS; E., Fattorusso | - | |
| Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore. | 1-gen-2007 | Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; B., Joshi; G., Kukreja; M., Persico; B., Catalanotti; E., Novellino; Fattorusso, E; Nacci, Vito; Savini, Luisa; D., Taramelli; N., Basilico; G., Morace; V., Yardley; C., Fattorusso | - | |
| Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains. | 1-gen-2006 | Gemma, Sandra; G., Kukreja; C., Fattorusso; M., Persico; Romano, MARIA PIA; Altarelli, Maria; Savini, Luisa; Campiani, Giuseppe; Fattorusso, E; N., Basilico; D., Taramelli; V., Yardley; Butini, Stefania | - | |
| Structural study of ribonucleotide reductase inhibitor hydrazones. Synthesis and X-ray diffraction analysis of a copper(II)-benzoylpyridine-2-quinolinyl hydrazone complex | 1-gen-2005 | Tamasi, Gabriella; Chiasserini, Luisa; Savini, Luisa; Sega, Alessandro; Cini, Renzo | - | |
| Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors. | 1-gen-2005 | Campiani, Giuseppe; Fattorusso, C; Butini, Stefania; Gaeta, A; Agnusdei, M; Gemma, Sandra; Persico, M; Catalanotti, B; Savini, Luisa; Nacci, Vito; Novellino, E; Holloway, Hw; Greig, Nh; Belinskaya, T; Fedorko, Jm; Saxena, A. | - | |
| Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663 | 1-gen-2005 | G., Maga; Gemma, Sandra; C., Fattorusso; G. A., Locatelli; Butini, Stefania; M., Persico; G., Kukreja; Romano, MARIA PIA; Chiasserini, Luisa; Savini, Luisa; E., Novellino; Nacci, Vito; S., Spadari; Campiani, Giuseppe | - | |
| New alpha-(N)-heterocyclichydrazones: evaluation of anticancer, anti-HIV and antimicrobial activity. | 1-gen-2004 | Savini, Luisa; Chiasserini, Luisa; Travagli, Valter; Pellerano, Cesare; Novellino, E.; Cosentino, S.; Pisano, M. B. | - | |
| Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors | 1-gen-2003 | Savini, L.; Gaeta, A.; Fattorusso, C.; Catalanotti, B.; Campiani, G.; Chiasserini, L.; Pellerano, C.; Novellino, E.; Mckissic, D.; Saxena, A. | - | |
| Novel and potent tacrine-related hetero- and homobivalent ligands for acetylcholinesterase and butyrylcholinesterase | 1-gen-2001 | Savini, Luisa; Campiani, Giuseppe; Gaeta, Alessandra; Pellerano, Cesare; Fattorusso, Caterina; Chiasserini, Luisa; Fedorko, James M.; Saxena, Ashima | - |
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