Sfoglia per Autore
Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides
2018-01-01 Tintori, Cristina; Iovenitti, Giulia; Ceresola, Elisa Rita; Ferrarese, Roberto; Zamperini, Claudio; Brai, Annalaura; Poli, Giulio; Dreassi, Elena; Cagno, Valeria; Lembo, David; Canducci, Filippo; Botta, Maurizio
Novel broad spectrum virucidal molecules against enveloped viruses
2018-01-01 Cagno, Valeria; Tintori, Cristina; Civra, Andrea; Cavalli, Roberta; Tiberi, Marika; Botta, Lorenzo; Brai, Annalaura; Poli, Giulio; Tapparel, Caroline; Lembo, David; Botta, Maurizio
COMPOUNDS AND USES THEREOF
2016-01-01 Botta, Maurizio; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Tintori, Cristina; Vignaroli, Giulia
Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents
2016-01-01 Brai, Annalaura; Fazi, Roberta; Tintori, Cristina; Zamperini, Claudio; Bugli, Francesca; Sanguinetti, Maurizio; Stigliano, Egidio; Esté, José; Badia, Roger; Franco, Sandra; Martinez, Miguel A.; Martinez, Javier P.; Meyerhans, Andreas; Saladini, Francesco; Zazzi, Maurizio; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio
Kuwanon-L as a New Allosteric HIV-1 Integrase Inhibitor: Molecular Modeling and Biological Evaluation
2015-01-01 Esposito, Francesca; Tintori, Cristina; Martini, Riccardo; Christ, Frauke; Debyser, Zeger; Ferrarese, Roberto; Cabiddu, Gianluigi; Corona, Angela; Ceresola, Elisa Rita; Calcaterra, Andrea; Iovine, Valentina; Botta, Bruno; Clementi, Massimo; Canducci, Filippo; Botta, Maurizio; Tramontano, Enzo
Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors
2015-01-01 Fazi, Roberta; Tintori, Cristina; Brai, Annalaura; Botta, Lorenzo; Selvaraj, Manikandan; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio
The fight against the influenza A virus H1N1: synthesis, molecular modeling, and biological evaluation of benzofurazan derivatives as viral RNA polymerase inhibitors.
2014-01-01 Pagano, Mafalda; Castagnolo, Daniele; Bernardini, Martina; Fallacara, Al; Laurenzana, Ilaria; Deodato, Davide; Kessler, U; Pilger, B; Stergiou, L; Strunze, S; Tintori, Cristina; Botta, Maurizio
2-Aminothiazolones as anti-hiv agents that act as gp120-cd4 inhibitors
2014-01-01 Tiberi, Marika; Tintori, Cristina; Ceresola, Elisa Rita; Fazi, Roberta; Zamperini, Claudio; Calandro, Pierpaolo; Franchi, Luigi; Selvaraj, Manikandan; Botta, Lorenzo; Sampaolo, Michela; Saita, Diego; Ferrarese, Roberto; Clementi, Massimo; Canducci, Filippo; Botta, Maurizio
Stereocontrolled synthesis of 5-azaspiro[2.3]hexane derivatives as conformationally "frozen" analogues of L-glutamic acid
2014-01-01 Bechi, Beatrice; Amantini, D.; Tintori, Cristina; Botta, Maurizio; Fabio, R. D.
Insight into the Allosteric Inhibition of Abl Kinase
2014-01-01 Fallacara, Anna Lucia; Tintori, Cristina; Radi, Marco; Schenone, Silvia; Botta, Maurizio
Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma.
2014-01-01 Tintori, Cristina; Fallacara, A. L.; Radi, Marco; Zamperini, Claudio; Dreassi, Elena; Crespan, E.; Maga, G.; Schenone, S.; Musumeci, F.; Brullo, C.; Richters, A.; Gasparrini, F.; Angelucci, A.; Festuccia, C.; Delle Monache, S.; Rauh, D.; Botta, M.
Protein-protein interactions and human cellular cofactors as new targets for HIV therapy
2014-01-01 Tintori, Cristina; Brai, Annalaura; Fallacara, ANNA LUCIA; Fazi, Roberta; Schenone, Silvia; Botta, Maurizio
High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction.
2014-01-01 Tintori, Cristina; Laurenzana, Ilaria; Fallacara, Al; Kessler, U; Pilger, B; Stergiou, L; Botta, Maurizio
A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors
2013-01-01 Mori, Mattia; Tintori, Cristina; Christopher, R. S. A.; Radi, M.; Schenone, S.; Musumeci, F.; Brullo, C.; Sanità, P.; Delle Monache, S.; Angelucci, A.; Kissova, M.; Crespan, E.; Maga, G.; Botta, M.
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant
2013-01-01 Botta, Maurizio; Tintori, Cristina; Musumeci, F.; Brullo, C.; Zamperini, Claudio; Dreassi, Elena; Fallacara, ANNA LUCIA; Vignaroli, Giulia; Crespan, E.; Zanoli, S.; Laurenzana, Ilaria; Filippi, I.; Maga, G.; Schenone, S.; Angelucci, A.; Botta, M.
Identification of Hck inhibitors as hits for the development of antileukemia and anti-HIV agents
2013-01-01 Tintori, C.; Laurenzana, I.; La Rocca, F.; Falchi, F.; Carraro, F.; Ruiz, A.; Esté, J. A.; Kissova, M.; Crespan, E.; Maga, G.; Biava, M.; Brullo, C.; Schenone, S.; Botta, M.
Probing the binding site of abl tyrosine kinase using in situ click chemistry
2013-01-01 Peruzzotti, C.; Borrelli, S.; Ventura, M.; Pantano, R.; Fumagalli, G.; Christodoulou, M. S.; Monticelli, D.; Luzzani, M.; Fallacara, A. L.; Tintori, Cristina; Botta, Maurizio; Passarella, D.
Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120
2013-01-01 Tintori, Cristina; Selvaraj, Manikandan; Badia, R.; Clotet, B.; Esté, J. A.; Botta, Maurizio
Discovery of small molecule HIV-1 integrase dimerization inhibitors.
2012-01-01 Tintori, Cristina; Demeulemeester, J; Franchi, L; Massa, S; Debyser, Z; Christ, F; Botta, Maurizio
Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling.
2012-01-01 Furlan, A.; Colombo, F.; Kover, A.; Issaly, N.; Tintori, Cristina; Angeli, Lucilla; Leroux, V.; Letard, S.; Amat, M.; Asses, Y.; Maigret, B.; Dubreuil, P.; Botta, Maurizio; Dono, R.; Bosch, J.; Piccolo, O.; Passarella, D.; Maina, F.
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides | 1-gen-2018 | Tintori, Cristina; Iovenitti, Giulia; Ceresola, Elisa Rita; Ferrarese, Roberto; Zamperini, Claudio; Brai, Annalaura; Poli, Giulio; Dreassi, Elena; Cagno, Valeria; Lembo, David; Canducci, Filippo; Botta, Maurizio | - | |
| Novel broad spectrum virucidal molecules against enveloped viruses | 1-gen-2018 | Cagno, Valeria; Tintori, Cristina; Civra, Andrea; Cavalli, Roberta; Tiberi, Marika; Botta, Lorenzo; Brai, Annalaura; Poli, Giulio; Tapparel, Caroline; Lembo, David; Botta, Maurizio | - | |
| COMPOUNDS AND USES THEREOF | 1-gen-2016 | Botta, Maurizio; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Tintori, Cristina; Vignaroli, Giulia | - | |
| Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents | 1-gen-2016 | Brai, Annalaura; Fazi, Roberta; Tintori, Cristina; Zamperini, Claudio; Bugli, Francesca; Sanguinetti, Maurizio; Stigliano, Egidio; Esté, José; Badia, Roger; Franco, Sandra; Martinez, Miguel A.; Martinez, Javier P.; Meyerhans, Andreas; Saladini, Francesco; Zazzi, Maurizio; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio | - | |
| Kuwanon-L as a New Allosteric HIV-1 Integrase Inhibitor: Molecular Modeling and Biological Evaluation | 1-gen-2015 | Esposito, Francesca; Tintori, Cristina; Martini, Riccardo; Christ, Frauke; Debyser, Zeger; Ferrarese, Roberto; Cabiddu, Gianluigi; Corona, Angela; Ceresola, Elisa Rita; Calcaterra, Andrea; Iovine, Valentina; Botta, Bruno; Clementi, Massimo; Canducci, Filippo; Botta, Maurizio; Tramontano, Enzo | - | |
| Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors | 1-gen-2015 | Fazi, Roberta; Tintori, Cristina; Brai, Annalaura; Botta, Lorenzo; Selvaraj, Manikandan; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio | - | |
| The fight against the influenza A virus H1N1: synthesis, molecular modeling, and biological evaluation of benzofurazan derivatives as viral RNA polymerase inhibitors. | 1-gen-2014 | Pagano, Mafalda; Castagnolo, Daniele; Bernardini, Martina; Fallacara, Al; Laurenzana, Ilaria; Deodato, Davide; Kessler, U; Pilger, B; Stergiou, L; Strunze, S; Tintori, Cristina; Botta, Maurizio | - | |
| 2-Aminothiazolones as anti-hiv agents that act as gp120-cd4 inhibitors | 1-gen-2014 | Tiberi, Marika; Tintori, Cristina; Ceresola, Elisa Rita; Fazi, Roberta; Zamperini, Claudio; Calandro, Pierpaolo; Franchi, Luigi; Selvaraj, Manikandan; Botta, Lorenzo; Sampaolo, Michela; Saita, Diego; Ferrarese, Roberto; Clementi, Massimo; Canducci, Filippo; Botta, Maurizio | - | |
| Stereocontrolled synthesis of 5-azaspiro[2.3]hexane derivatives as conformationally "frozen" analogues of L-glutamic acid | 1-gen-2014 | Bechi, Beatrice; Amantini, D.; Tintori, Cristina; Botta, Maurizio; Fabio, R. D. | - | |
| Insight into the Allosteric Inhibition of Abl Kinase | 1-gen-2014 | Fallacara, Anna Lucia; Tintori, Cristina; Radi, Marco; Schenone, Silvia; Botta, Maurizio | - | |
| Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma. | 1-gen-2014 | Tintori, Cristina; Fallacara, A. L.; Radi, Marco; Zamperini, Claudio; Dreassi, Elena; Crespan, E.; Maga, G.; Schenone, S.; Musumeci, F.; Brullo, C.; Richters, A.; Gasparrini, F.; Angelucci, A.; Festuccia, C.; Delle Monache, S.; Rauh, D.; Botta, M. | - | |
| Protein-protein interactions and human cellular cofactors as new targets for HIV therapy | 1-gen-2014 | Tintori, Cristina; Brai, Annalaura; Fallacara, ANNA LUCIA; Fazi, Roberta; Schenone, Silvia; Botta, Maurizio | - | |
| High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction. | 1-gen-2014 | Tintori, Cristina; Laurenzana, Ilaria; Fallacara, Al; Kessler, U; Pilger, B; Stergiou, L; Botta, Maurizio | - | |
| A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors | 1-gen-2013 | Mori, Mattia; Tintori, Cristina; Christopher, R. S. A.; Radi, M.; Schenone, S.; Musumeci, F.; Brullo, C.; Sanità, P.; Delle Monache, S.; Angelucci, A.; Kissova, M.; Crespan, E.; Maga, G.; Botta, M. | - | |
| Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant | 1-gen-2013 | Botta, Maurizio; Tintori, Cristina; Musumeci, F.; Brullo, C.; Zamperini, Claudio; Dreassi, Elena; Fallacara, ANNA LUCIA; Vignaroli, Giulia; Crespan, E.; Zanoli, S.; Laurenzana, Ilaria; Filippi, I.; Maga, G.; Schenone, S.; Angelucci, A.; Botta, M. | - | |
| Identification of Hck inhibitors as hits for the development of antileukemia and anti-HIV agents | 1-gen-2013 | Tintori, C.; Laurenzana, I.; La Rocca, F.; Falchi, F.; Carraro, F.; Ruiz, A.; Esté, J. A.; Kissova, M.; Crespan, E.; Maga, G.; Biava, M.; Brullo, C.; Schenone, S.; Botta, M. | - | |
| Probing the binding site of abl tyrosine kinase using in situ click chemistry | 1-gen-2013 | Peruzzotti, C.; Borrelli, S.; Ventura, M.; Pantano, R.; Fumagalli, G.; Christodoulou, M. S.; Monticelli, D.; Luzzani, M.; Fallacara, A. L.; Tintori, Cristina; Botta, Maurizio; Passarella, D. | - | |
| Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120 | 1-gen-2013 | Tintori, Cristina; Selvaraj, Manikandan; Badia, R.; Clotet, B.; Esté, J. A.; Botta, Maurizio | - | |
| Discovery of small molecule HIV-1 integrase dimerization inhibitors. | 1-gen-2012 | Tintori, Cristina; Demeulemeester, J; Franchi, L; Massa, S; Debyser, Z; Christ, F; Botta, Maurizio | - | |
| Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling. | 1-gen-2012 | Furlan, A.; Colombo, F.; Kover, A.; Issaly, N.; Tintori, Cristina; Angeli, Lucilla; Leroux, V.; Letard, S.; Amat, M.; Asses, Y.; Maigret, B.; Dubreuil, P.; Botta, Maurizio; Dono, R.; Bosch, J.; Piccolo, O.; Passarella, D.; Maina, F. | - |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile